The Role of Genetics and Oxidative Stress in the Etiology of Male Infertility —A Unifying Hypothesis?

We present a hypothesis whereby a number of environmental, lifestyle and clinical factors conspire to induce oxidative DNA damage in the male germ line which then triggers the formation de novo mutations which can have a major impact on the health of the offspring including their subsequent fertility.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research