Down syndrome identified in 2600-year-old infants through their DNA
Between 770 and 550 B.C.E., in a hilltop village called Alto de la Cruz near the modern Spanish city of Navarro, one infant girl received an unusual burial: Although people in Iron Age Spain usually cremated their dead, the girl was laid to rest beneath the floors of an elaborately decorated dwelling, with grave goods including bronze rings, a shell from the Mediterranean, and three whole sheep or goats.
And she wasn’t alone: Archaeologists working in the 1940s and ’50s found dozens of infants buried below the floors in Alto de la Cruz and another nearby village built more than 2600 years ago. “The main questio...
Source: ScienceNOW - February 20, 2024 Category: Science Source Type: news
What Is the Life Expectancy of a Person With Klinefelter Syndrome?
Title: What Is the Life Expectancy of a Person With Klinefelter Syndrome?Category: Diseases and ConditionsCreated: 9/13/2021 12:00:00 AMLast Editorial Review: 9/13/2021 12:00:00 AM (Source: MedicineNet Kids Health General)
Source: MedicineNet Kids Health General - September 13, 2021 Category: Pediatrics Source Type: news
1,000-year-old remains in Finland may be non-binary iron age leader
DNA suggests body buried in feminine attire with swords had Klinefelter syndrome, researchers sayModern analysis of a 1,000-year-old grave in Finland challenges long-held beliefs about gender roles in ancient societies, and may suggest non-binary people were not only accepted but respected members of their communities, researchers have said.According to a peer-reviewedstudy in the European Journal of Archaeology, DNA analysis of remains in a late iron age grave at Suontaka Vesitorninm äki in Hattula, southern Finland, may have belonged to a high-status non-binary person.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - August 9, 2021 Category: Science Authors: Jon Henley Tags: Archaeology Finland Gender World news Europe Science Source Type: news
Major Symptoms of Klinefelter Syndrome
What Are the Major Symptoms of Klinefelter Syndrome? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - May 31, 2020 Category: General Medicine Source Type: news
Hypogonadism | Medscape Hypogonadism | Medscape
Male hypogonadism, or testosterone deficiency, results either from a disorder of the testes (primary hypogonadism) or of the hypothalamus or pituitary glands (secondary hypogonadism). Causes of primary hypogonadism include Klinefelter ' s syndrome, undescended testicles, and hemochromatosis. Secondary hypogonadism can be due to aging, increasing body mass index, and/or type 2 diabetes mellitus. (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 4, 2019 Category: Consumer Health News Tags: Resource Center Source Type: news
Klinefelter syndrome: many men have an extra X chromosome – but it is rarely diagnosed
The genetic condition is one of the most common in the UK and may be a leading cause of infertility in men. Why does it so often go untreated?Three years ago, Paul (not his real name), now 31, went to the doctor with stomach pains. His blood test came back with low testosterone levels. “We went to see a urologist and he said bluntly that we wouldn’t have any options to have kids with my sperm – we would have to use a donor or adopt,” he says. “My wife immediately burst into tears.” The couple had been trying for a child since they married in 2015. Paul was also devasta ted. “It put so much stress on me, becau...
Source: Guardian Unlimited Science - August 26, 2019 Category: Science Authors: Ammar Kalia Tags: Health & wellbeing Genetics Biology Science Fertility problems Society Source Type: news
Sexual identity disorder and psychosis in Klinefelter syndrome: a synthesis of literature and a case report - Maillefer A, Sabe M, Coste C, Bartolomei J, Jaafar J, Sentissi O.
Klinefelter syndrome (KS) 47, XXY is the most frequent chromosomal abnormality causing hypogonadism in humans. This chromosomal abnormality of number in its classical form called homogeneous (supernumerary X) is generally the result of a meiosis accident. ... (Source: SafetyLit)
Source: SafetyLit - January 25, 2019 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
The Idea of a ‘DNA Test’ for Transgender People Is Part of a Long, Dark History
Science is too busy holding the universe together to care about politics. Greenhouse gases will continue contributing to climate change and vaccines will continue not causing autism, whether you believe it or not.
None of that means that politicians and ideologues won’t keep trying to drag science into their fights. The latest example of this unlovely truth occurred just this week, when the New York Times reported the existence of a memo drafted by the Department of Health and Human Services that would, if the changes it details were implemented, effectively roll back civil protections for transgender people by defin...
Source: TIME: Science - October 25, 2018 Category: Science Authors: Jeffrey Kluger Tags: Uncategorized LGBTQ onetime Science sexism Source Type: news
Medical News Today: Klinefelter syndrome: Symptoms, diagnosis, and management
Klinefelter syndrome is a disorder affecting the genes in men. Learn about Klinefelter syndrome, how it is diagnosed, its symptoms, and treatment options. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 2, 2017 Category: Consumer Health News Tags: Men's Health Source Type: news
Unique Characteristics of the X Chromosome and Related Disorders
This article reviews these unique characteristics and applies their guiding principles in a broad overview to Klinefelter syndrome, ornithine transcarbamylase (OTC) deficiency, hemophilia, and fragile X syndrome. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - March 31, 2017 Category: Pediatrics Authors: Shah, K., DeRemigis, A., Hageman, J. R., Sriram, S., Waggoner, D. Tags: Pediatric Drug Labeling Update Articles Source Type: news
In Klinefelter Syndrome Patients, What are the Common Behavioral Problems?
Discussion
Klinefelter syndrome (KS) is a common genetic abnormaly with a prevalence of 1 in ~650 male births. It was first described in 1942 by Dr. Harry Klinefelter. It is associated with at least one extra X chromosome with the most common karyotype (~80% of patients) being 47 XXY. Other karyotypes are seen along with mosaicism. It is believed that although it is very prevalent, only about 25-33% of people with KS are identified. About 10% are identified before puberty with the rest usually identified because of hypogonadism and tall stature especially in teenage years or due to infertility in adulthood. KS is diagnosed...
Source: PediatricEducation.org - August 29, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
What Medical Problems Can Patients with Turner Syndrome Have?
Discussion
Turner Syndrome (TS) is one of the most common genetic disorders in females. It was first described by Dr. Henry H. Turner in 1938. It affects 1 in 2000-2500 births and ~70,000 girls and women have TS in the United States. It is caused by the absence of all or part of the second X chromosome. The most common variation is 45X which affects about 50% of TS patients and usually has the most complications, but there are other variations. Phenotypes vary and therefore the age of diagnosis varies. Mean age of diagnosis unfortunately is 15 years. Diagnosis is made by chromosomal analysis. Haploinsufficiency of the SHOX...
Source: PediatricEducation.org - August 15, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Klinefelter syndrome 47,XXY - Male Breast...
Klinefelter syndrome is a rare genetic condition in which a man has an extra X chromosome. (Males usually have one X and one Y chromosome.) Some of the other conditions associated with Klinefelter are hypothyroidism, infertility, testicular cancer, and an increased risk for male breast cancer. (Source: About.com Breast Cancer)
Source: About.com Breast Cancer - March 28, 2016 Category: Cancer & Oncology Authors: breastcancer.guide at about.com Tags: health Source Type: news
Gynecomastia and Klinefelter SyndromeGynecomastia and Klinefelter Syndrome
Gain a better understanding of the relationship between these two conditions, and find out the available options for the surgical correction of gynecomastia. ePlasty, Open Access Journal of Plastic Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 16, 2016 Category: Consumer Health News Tags: Plastic Surgery & Aesthetic Medicine Journal Article Source Type: news
Detecting Klinefelter Syndrome Disorder in Boys
A new assessment tool is being developed by researchers at Columbia University Medical Center (CUMC) to help pediatricians detect the physical traits of the syndrome. The tool could pave the way for early interventions that prevent and treat a range of physical, psychological, social, and cognitive impairments. The study was published in The Journal of Pediatrics. (Source: Disabled World)
Source: Disabled World - September 2, 2015 Category: Disability Tags: Medical Research Source Type: news
