Gynecomastia and Klinefelter SyndromeGynecomastia and Klinefelter Syndrome

Gain a better understanding of the relationship between these two conditions, and find out the available options for the surgical correction of gynecomastia. ePlasty, Open Access Journal of Plastic Surgery
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Plastic Surgery & Aesthetic Medicine Journal Article Source Type: news

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We describe a 65-year-old man who presented with arthralgia, reduced body hair and gynecomastia. He showed severe pancytopaenia. Laboratory examination revealed high follicle-stimulating hormone, low testosterone and oestradiol, elevated antinuclear antibodies, anti-dsDNA and ESR levels, as well as low complement levels. An electrocardiogram showed atrial fibrillation. Computed tomography and dual-energy x-ray absorptiometry showed pleural effusion and osteoporosis. Chromosome analysis revealed 47, XXY karyotype. The unifying diagnosis was therefore Klinefelter's syndrome (KS) with systemic lupus erythematosus (SLE), with ...
Source: Lupus - Category: Rheumatology Authors: Tags: Lupus Source Type: research
ConclusionThis large retrospective cohort study suggests that patients who used PPIs are at higher risk of developing gynecomastia. Clinicians may want to convey this information to male patients who require long ‐term PPI therapy.This article is protected by copyright. All rights reserved.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: Brief Report Source Type: research
Klinefelter syndrome (KS) is characterized by the presence of at least one supernumerary X chromosome. KS typical symptoms include tall stature, gynecomastia, hypogonadism and azoospermia. KS patients show a h...
Source: BMC Medical Genetics - Category: Genetics & Stem Cells Authors: Tags: Research article Source Type: research
Klinefelter syndrome (KS) is a highly prevalent sex chromosome aneuploidy condition that affects up to 1 in 450 male births (Herlihy et al., 2011). The majority of affected males exhibit a 47,XXY karyotype, although more than one supernumerary X chromosome is sometimes observed (Rey et al., 2011, Boada et al., 2009). The physical phenotype typically includes tall stature, hypogonadism, reduced testosterone, infertility and gynecomastia. Features comprising the behavioral phenotype include mood symptoms and deficits in specific domains of cognitive function, predominantly language, learning and memory, and executive functio...
Source: Psychoneuroendocrinology - Category: Psychiatry Authors: Source Type: research
This report also highlights the fact that the percentage of patients with dysphoria, which is much higher among the Klinefelter syndromes in the literature, might be due to the lack of testosterone treatment. This atypical and uncommon observation could be sought at larger scales in patients with fluctuating dysphoria. Finally and more broadly, it also recalls the importance of researching the total testosterone levels of patients suffering from dysphoria, which do not suffer from a psychiatric pathology.
Source: Sexologies - Category: Sexual Medicine Source Type: research
This report also highlights the fact that the percentage of patients with dysphoria, which is much higher among the Klinefelter syndromes in the literature, might be due to the lack of testosterone treatment. This atypical and uncommon observation could be sought at larger scales in patients with fluctuating dysphoria. Finally and more broadly, it also recalls the importance of researching the total testosterone levels of patients suffering from dysphoria, which do not suffer from a psychiatric pathology.
Source: Sexologies - Category: Sexual Medicine Source Type: research
This report also highlights the fact that the percentage of patients with dysphoria, which is much higher among the Klinefelter syndromes in the literature, might be due to the lack of testosterone treatment. This atypical and uncommon observation could be sought at larger scales in patients with fluctuating dysphoria. Finally and more broadly, it also recalls the importance of researching the total testosterone levels of patients suffering from dysphoria, which do not suffer from a psychiatric pathology.
Source: Sexologies - Category: Sexual Medicine Source Type: research
This report also highlights the fact that the percentage of patients with dysphoria, which is much higher among the Klinefelter syndromes in the literature, might be due to the lack of testosterone treatment. This atypical and uncommon observation could be sought at larger scales in patients with fluctuating dysphoria. Finally and more broadly, it also recalls the importance of researching the total testosterone levels of patients suffering from dysphoria, which do not suffer from a psychiatric pathology.
Source: Sexologies - Category: Sexual Medicine Source Type: research
This report also highlights the fact that the percentage of patients with dysphoria, which is much higher among the Klinefelter syndromes in the literature, might be due to the lack of testosterone treatment. This atypical and uncommon observation could be sought at larger scales in patients with fluctuating dysphoria. Finally and more broadly, it also recalls the importance of researching the total testosterone levels of patients suffering from dysphoria, which do not suffer from a psychiatric pathology.
Source: Sexologies - Category: Sexual Medicine Source Type: research
This report also highlights the fact that the percentage of patients with dysphoria, which is much higher among the Klinefelter syndromes in the literature, might be due to the lack of testosterone treatment. This atypical and uncommon observation could be sought at larger scales in patients with fluctuating dysphoria. Finally and more broadly, it also recalls the importance of researching the total testosterone levels of patients suffering from dysphoria, which do not suffer from a psychiatric pathology.
Source: Sexologies - Category: Sexual Medicine Source Type: research
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