Molecular Correlates of Topiramate and GRIK1 rs2832407 Genotype in Pluripotent Stem Cell-Derived Neural Cultures.

CONCLUSIONS: This work highlights the use of iPSC technologies to study pharmacogenetic treatment effects in psychiatric disorders and furthers our understanding of the molecular effects of topiramate exposure in human neural cells.
PMID: 32574382 [PubMed - as supplied by publisher]

Source: Alcoholism, Clinical and Experimental Research - June 22, 2020 Category: Addiction Authors: Lieberman R, Jensen KP, Clinton K, Levine ES, Kranzler HR, Covault J Tags: Alcohol Clin Exp Res Source Type: research