The impact of calorie-limited diets on the detectability of renal cell carcinomas by positron emission tomography with 2-deoxy-2-18F-fluoro-D-glucose

Conclusions: Our study demonstrates that CRD significantly increased the tumor/normal tissue PET signal ratio in fumarase-deficient XP152 PDX in NOD-SCID mice, which suggests the potential of using CRD to enhance the detectability of [18F]FDG-PET of RCC tumors in clinical diagnosis and treatment assessment. Acknowledgements: This work was partially supported by grants from the Cancer Prevention and Research Institute of Texas (RP170638) and NIH (P50 CA196516).

Source: Journal of Nuclear Medicine - May 14, 2020 Category: Nuclear Medicine Authors: Wu, C.-Y., Lo, S.-T., Velazquez, A., Pennington, J., Woolford, L., Brugarolas, J., Sun, X. Tags: Basic Oncology & amp; Translational (Poster Session) Source Type: research