Safety of vaginal estrogens: a systematic review

Conclusions: Newer low-dose estradiol rings, tablets, and inserts appear to induce the least increases in serum hormones, possibly indicating greater safety. Limited evidence in trials lasting up to 52 weeks suggest endometrial safety of vaginal estrogen use. Long-term trials are needed. Video Summary:http://links.lww.com/MENO/A513.
Source: Menopause - Category: OBGYN Tags: Review Articles Source Type: research