Feeling Blue? Sunday Sadness Is A Real Thing

By Sandee LaMotte, CNN (CNN) — Many of us begin to groan and moan as our precious weekend comes to an end. It’s not just the interruption of fun with friends and family that triggers the Sunday blues, or what some call the Sunday scaries. It’s also anxiety and dread about the workweek to come. One study found 81% of more than 1,000 respondents said they became progressively more anxious as their restful Sunday came to a close. Psychologists call it “anticipatory anxiety.” Nearly two-thirds reported a restless night’s sleep Sunday night, which they attributed to job-related anxiety. And it’s not just because people hate their jobs: Even people who said they love their work reported anxiety over job expectations and workload. How we get stressed Fretting over something can trigger our flight-or-fight reflex, which floods the body with adrenaline. Pulse rate and blood pressure rise. Breathing becomes rapid, and the extra oxygen in the brain increases alertness. Blood sugars and other nutrients flood the bloodstream, supplying a boost of energy. If the brain continues to think the danger is there (cue work worries) the body keeps systems on high, triggering the release of cortisol, the body’s main stress hormone. A continuous flood of cortisol keeps us revved up and on high alert. You want to counter that stress by doing things that boost endorphins — the feel-good neurotransmitters in the brain that act as natural p...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Featured Health News CNN Mental Health Source Type: news

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Publication date: Available online 14 November 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): S. Gentile, F. Strollo, E. Satta, T. Della-Corte, C. Romano, G. Guarino, Nefrocenter Research Study Group: Nephrologists, Diabetologists, NursesSummaryDiabetes Mellitus (DM) is the most common cause of renal failure and ESRD all over the world, and often requires an individualized insulin treatment regimen. Malnutrition, depression-related eating behavior changes, high on-off-dialysis day-to-day glycemic variability and frequent hypoglycemic events occurring during or immediately after dialy...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: Available online 14 November 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Mahdieh Sedighi Pashaki, Jamal Asad Mezel, Zahra Mokhtari, Reza Ghanei Gheshlagh, Parisa Shahbazi Hesabi, Taban Nematifard, Soore KhakiAbstractDepression is one of the most common psychiatric disorders in patients with diabetes, which can exacerbate and accelerate adverse diabetes complaints by reducing self-care behaviors and medication adherence. The purpose of this study is to estimate the prevalence of depression in Iranian patients with diabetes. The search was conducted in the database...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionHigh prevalences of underweight and overweight/obesity were identified in ASEAN countries and several correlates were identified which can help to tailor interventions.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
In this study, we have used a novel DNAzyme based approach to create a larval model of FXS in zebrafish with specific focus on the early developmental window.MethodsFmr1specific DNAzymes were electroporated into embryos to create theknockdown. Changes in RNA and protein levels of FMRP and relevant biomarkers were measured in the 0-7dpf window. Behavioral tests to measure anxiety, cognitive impairments and irritability in the larvae were conducted at the 7dpf stage. Drug treatment was carried out at various time points in the 0-7dpf window to identify the critical window for pharmacological intervention.ResultsThe DNAzyme b...
Source: Journal of Pharmacological and Toxicological Methods - Category: Drugs & Pharmacology Source Type: research
Shalaka S. Ramgir and V. G. Abilash*
Source: Indian Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Source Type: research
ConclusionsThis study showed that three EFT sessions administered in a group setting, reduced and helped them better cope with exam anxiety as well as other anxiety indicators in nursing students.
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
This study aimed to investigate the risk behaviors of adolescents with T1D and the effect of orthorexic eating behaviors (OEB) on glycemic control (GC). Methods: This cross-sectional study was conducted with 107 adolescents with T1D who were between 13-18 years of age and attended high school. The risk behavior scale (RBS) and orthorexic behavior scale (ORTO-11) were administered to the participants. A high RBS score indicates risky behavior; a low ORTO-11 score suggests a tendency to OEB. At the same time, participants were tested for GC and categorized as optimal GC (HbA1c ≤7%) or poor GC (HbA1c>7%). Result...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
Publication date: Available online 15 November 2019Source: Autoimmunity ReviewsAuthor(s): José María G. Ruiz de Morales, Lluís Puig, Esteban Daudén, Juan D. Cañete, José Luis Pablos, Antonio Olveira Martín, Carlos González Juanatey, Alfredo Adán, Xavier Montalbán, Natalia Borruel, Guillermo Ortí, Esther Holgado Martín, Carolina García-Vidal, Cynthia Vizcaya Morales, Víctor Martín Vázquez, Miguel Ángel González-GayAbstractInterleukin 17 (IL-17) is a proinflammatory cytokine that has been the focus of...
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
Ryan R. Kelly1,2†, Lindsay T. McDonald1,2†, Nathaniel R. Jensen1,2, Sara J. Sidles1,2 and Amanda C. LaRue1,2* 1Research Services, Ralph H. Johnson VA Medical Center, Charleston, SC, United States 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, United States The significant biochemical and physiological effects of psychological stress are beginning to be recognized as exacerbating common diseases, including osteoporosis. This review discusses the current evidence for psychological stress-associated mental health disorders as risk factors for os...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusion: Suvorexant treatment resulted in overall improvement in the quality of sleep and the severity of anxiety and depression. This dual orexin antagonist may be related to autonomic functions and neuroendocrine systems, especially in the hypothalamus-pituitary-adrenal axis in psychiatric subjects. Introduction The hypothalamus plays a critical role in the integrated control of sleep/wakefulness, thermogenesis, and energy homeostasis, and the lateral hypothalamus area (LHA) in this region has been regarded as an important center for arousal and feeding.[1] The neuropeptide orexin A and orexin B (also known as hypocre...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Anxiety Disorders Current Issue Depression Original Research Psychiatry Psychopharmacology Sleep Disorders Autonomic nervous insomnia neuroendocrine orexin antagonist suvorexant Source Type: research
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