The future of cystic fibrosis care: a global perspective

Publication date: Available online 27 September 2019Source: The Lancet Respiratory MedicineAuthor(s): Scott C Bell, Marcus A Mall, Hector Gutierrez, Milan Macek, Susan Madge, Jane C Davies, Pierre-Régis Burgel, Elizabeth Tullis, Claudio Castaños, Carlo Castellani, Catherine A Byrnes, Fiona Cathcart, Sanjay H Chotirmall, Rebecca Cosgriff, Irmgard Eichler, Isabelle Fajac, Christopher H Goss, Pavel Drevinek, Philip M Farrell, Anna M GravelleExecutive summaryThe past six decades have seen remarkable improvements in health outcomes for people with cystic fibrosis, which was once a fatal disease of infants and young children. However, although life expectancy for people with cystic fibrosis has increased substantially, the disease continues to limit survival and quality of life, and results in a large burden of care for people with cystic fibrosis and their families. Furthermore, epidemiological studies in the past two decades have shown that cystic fibrosis occurs and is more frequent than was previously thought in populations of non-European descent, and the disease is now recognised in many regions of the world. The Lancet Respiratory Medicine Commission on the future of cystic fibrosis care was established at a time of great change in the clinical care of people with the disease, with a growing population of adult patients, widespread genetic testing supporting the diagnosis of cystic fibrosis, and the development of therapies targeting defects in the cystic fibrosis transmem...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research