Popular heartburn drug ranitidine recalled: What you need to know and do

If you or a family member take ranitidine (Zantac) to relieve heartburn, you may have heard that the FDA has found a probable human carcinogen (a substance that could cause cancer) in it. The story is unfolding quickly and many details remain murky. Here is what we know so far and what you should do. What do we know so far? On September 13, 2019, the FDA announced that preliminary tests found low levels of N-nitrosodimethylamine (NDMA) in ranitidine, a heartburn medication used by millions of Americans. This week, the drug companies Novartis (through its generic division, Sandoz) and Apotex announced that they were recalling all of their generic ranitidine products sold in the US. These announcements came after a Connecticut-based online pharmacy informed the FDA that it had detected NDMA in multiple ranitidine products under certain test conditions. What is ranitidine and which products are affected? Ranitidine (also known by its brand name, Zantac, which is sold by the drug company Sanofi) is available both over the counter (OTC) and by prescription. It belongs to the class of drugs known as H2 (or histamine-2) blockers. OTC ranitidine is commonly used to relieve and prevent heartburn. Prescription strengths are also used to treat and prevent more serious ulcers in the stomach and intestines. Multiple companies sell generic versions of both the OTC and prescription products. So far, only Novartis/Sandoz and Apotex have recalled products. Ranitidine distributed by other comp...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Digestive Disorders Drugs and Supplements Health Source Type: blogs

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Authors: Reissier S, Cattoir V Abstract INTRODUCTION: Streptogramins (pristinamycin and quinupristin-dalfopristin) can be interesting options for the treatment of infections due to Gram-positive cocci, especially multidrug-resistant isolates. AREAS COVERED: This review provides an updated overview on structural and activity characteristics, mechanisms of action and resistance, pharmacokinetic/pharmacodynamic and clinical use of streptogramins. EXPERT OPINION: The streptogramin antibiotics act by inhibition of the bacterial protein synthesis. They are composed of two chemically distinct compounds, namely typ...
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
Publication date: 15 February 2021Source: Journal of Hazardous Materials, Volume 404, Part BAuthor(s): Yanhua Liu, Yang Li, Shanshan Dong, Lu Han, Ruixin Guo, Yourong Fu, Shenghu Zhang, Jianqiu Chen
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
Authors: Musio F Abstract INTRODUCTION: Anemia has and will continue to be a central theme in medicine particularly as clinicians are treating a burgeoning population of complex multi-organ system processes. As a result of multiple randomized controlled trials (RCTs), meta-analyses, and societal recommendations overly restrictive paradigms and under-administration of erythropoiesis stimulating agents (ESAs) have likely been followed by clinicians among all specialties. AREAS COVERED: A review of anemia in the context of chronic kidney disease, hematologic malignancies and cancer is presented with focus on the e...
Source: Expert Review of Hematology - Category: Hematology Tags: Expert Rev Hematol Source Type: research
Most people know about the damaging effects that binge drinking can bring to someone’s life. Loss of enjoyment of life, losing family relationships, financial and career struggles, homelessness, and legal consequences are just the tip of the iceberg. However, it can be more difficult to realize the long-term effect of binge drinking on the body, because you cannot always see it. Frequent binge drinking poses many dangerous health risks, and many of them can lead to death. Facts on Long-Term Effect of Binge Drinking on the Body For men, binge drinking is defined as consuming five or more drinks within about two hour...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcohol Rehab Information Alcoholism alcohol abuse alcohol dependence alcohol treatment alcohol treatment center binge binge drinking Source Type: blogs
If you or a family member take ranitidine (Zantac) to relieve heartburn, you may have heard that the FDA has found a probable human carcinogen (a substance that could cause cancer) in it. The story is unfolding quickly and many details remain murky. Here is what we know so far and what you should do. What do we know so far? On September 13, 2019, the FDA announced that preliminary tests found low levels of N-nitrosodimethylamine (NDMA) in ranitidine, a heartburn medication used by millions of Americans. This week, the drug companies Novartis (through its generic division, Sandoz) and Apotex announced that they were recalli...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Digestive Disorders Drugs and Supplements Health Source Type: blogs
Conclusion: Overall, Amenity Health has created a very high quality product in their MedCline Reflux Relief System. It effectively prevents reflux and is, in my opinion, more comfortable than the more traditional wedges on the market. However, higher...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive GI Medicine Source Type: blogs
Conclusion PPIs are commonly used medicines for acid reflux. This may seem like alarming news for the many people in the UK who take them, but it's important to remember that the overall risk of stomach cancer is still very low. This study has several limitations that mean we should be cautious about the results: This type of study can't prove PPIs caused the increased risk of cancer. The increased risk could be down to other factors. Researchers were unable to adjust their figures to take account of some relevant confounding factors, such as alcohol and tobacco use, as these weren't routinely recorded. Almost all the pati...
Source: NHS News Feed - Category: Consumer Health News Tags: Cancer Source Type: news
Conclusion This prospective cohort study aimed to see whether a test performed on patients with non-cancerous Barrett's oesophagus may be able to predict whether the condition progressed to oesophageal cancer.  Overall, they found genetic diversity in the oesophageal cell samples at the start of the study seemed to be linked to the risk of cancer progression. However, the research has limitations to consider: By design, this study is only able to draw links – it does not propose treatment or lifestyle steps to be taken to reduce risk. The sample of patients in this study is small, so we...
Source: NHS News Feed - Category: Consumer Health News Tags: Cancer Genetics/stem cells Source Type: news
Every time I come back to Africa, I’m reminded just how natural the health care is here. I recently watched one local herbalist cure a patient of chronic heartburn with a tea made from a popular root (more about that soon). Heartburn is a common disorder of the stomach caused by the overproduction of stomach acid. In America, mainstream medicine is likely throwing Big Pharma’s “treatments” at you — like proton-pump inhibitors (PPIs), which block the production of stomach acid. You might know these better as Nexium, Prilosec and Prevacid. But these PPIs have some pretty BIG downsides you&rsquo...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Natural Cures heartburn Remedies stomach acid Source Type: news
ConclusionGastroesophageal reflux does not appear to play a role in development of head and neck cancer. Level of Evidence3b. Laryngoscope, 2015
Source: The Laryngoscope - Category: ENT & OMF Authors: Tags: Head and Neck Source Type: research
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