Thoracic spinal cord neuromodulation obtunds dorsal root ganglion afferent neuronal transduction of the ischemic ventricle.
Conclusion: SCS obtunds the capacity of DRG ventricular neurites to transduce the ischemic myocardium to second order spinal neurons; a mechanism that would blunt reflex sympatho-excitation to myocardial ischemic stress, thereby contributing to its capacity to cardioprotect.
PMID: 31538809 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Heart and Circulatory Physiology - Category: Physiology Authors: Salavatian S, Ardell SM, Hammer M, Gibbons DD, Armour JA, Ardell JL Tags: Am J Physiol Heart Circ Physiol Source Type: research
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