Thoracic spinal cord neuromodulation obtunds dorsal root ganglion afferent neuronal transduction of the ischemic ventricle.

Conclusion: SCS obtunds the capacity of DRG ventricular neurites to transduce the ischemic myocardium to second order spinal neurons; a mechanism that would blunt reflex sympatho-excitation to myocardial ischemic stress, thereby contributing to its capacity to cardioprotect. PMID: 31538809 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Heart and Circulatory Physiology - Category: Physiology Authors: Tags: Am J Physiol Heart Circ Physiol Source Type: research