Treating stroke patients just 15 minutes earlier can save lives

Initiating stroke treatment just 15 minutes faster can save lives and prevent disability, according to a new UCLA-led study, published today inJAMA. The research also determined that busier hospitals — those that treat more than 450 people for stroke each year — have better outcomes than those that treat fewer than 400 stroke patients per year.Researchers at the  David Geffen School of Medicine at UCLA and five other institutions in the U.S. and Canada, examined data for 6,756 people who experienced ischemic strokes. The patients ’ median age was 71, and 51.2% were women.The researchers looked at stroke patients ’ treatment results in light of their “door-to-puncture” time — that is, the interval from their arrival at the hospital to the time their treatment began.The data showed that for every 1,000 people whose door-to-puncture time was 15 minutes sooner, 15 fewer died or were discharged to hospice care, 17 more were able to walk out of the hospital without assistance and 22 more could care for themselves after being discharged from the hospital. Researchers found that patients ’ median time from arriving at the hospital to the beginning of treatment was one hour, 27 minutes, and the median time from the onset of symptoms to treatment was three hours, 50 minutes.All of the patients in the study were treated with endovascular reperfusion therapy, which is used to treat strokes caused by a blockage in one of the major arter...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news

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Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak World news US news UK news Australia news South Africa Brazil Science Infectious diseases Source Type: news
We describe the performance of the apnea test without disconnection from the mechanical ventilator in two patients. The first case involved an 8-year-old boy admitted with severe hypoxemia due to pneumonia. He presented with cardiorespiratory arrest, followed by unresponsive coma due to hypoxic-ischemic encephalopathy. Two clinical exams revealed the absence of brainstem reflexes, and transcranial Doppler ultrasound revealed brain circulatory arrest. Three attempts were made to perform the apnea test, which were interrupted by hypoxemia; therefore, the apnea test was performed without disconnection from the mechanical vent...
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
We describe the performance of the apnea test without disconnection from the mechanical ventilator in two patients. The first case involved an 8-year-old boy admitted with severe hypoxemia due to pneumonia. He presented with cardiorespiratory arrest, followed by unresponsive coma due to hypoxic-ischemic encephalopathy. Two clinical exams revealed the absence of brainstem reflexes, and transcranial Doppler ultrasound revealed brain circulatory arrest. Three attempts were made to perform the apnea test, which were interrupted by hypoxemia; therefore, the apnea test was performed without disconnection from the mechanical vent...
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
We describe the performance of the apnea test without disconnection from the mechanical ventilator in two patients. The first case involved an 8-year-old boy admitted with severe hypoxemia due to pneumonia. He presented with cardiorespiratory arrest, followed by unresponsive coma due to hypoxic-ischemic encephalopathy. Two clinical exams revealed the absence of brainstem reflexes, and transcranial Doppler ultrasound revealed brain circulatory arrest. Three attempts were made to perform the apnea test, which were interrupted by hypoxemia; therefore, the apnea test was performed without disconnection from the mechanical vent...
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
We describe the performance of the apnea test without disconnection from the mechanical ventilator in two patients. The first case involved an 8-year-old boy admitted with severe hypoxemia due to pneumonia. He presented with cardiorespiratory arrest, followed by unresponsive coma due to hypoxic-ischemic encephalopathy. Two clinical exams revealed the absence of brainstem reflexes, and transcranial Doppler ultrasound revealed brain circulatory arrest. Three attempts were made to perform the apnea test, which were interrupted by hypoxemia; therefore, the apnea test was performed without disconnection from the mechanical vent...
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
Abstract To evaluate functional capacity, mobility and balance in elderly patients with Alzheimer's Disease (AD), in its mild, moderate and severe forms, verifying the existence of correlation among these parameters. Eighty-eight elderly patients (81.79 ± 6.54 years) diagnosed with AD treated at an elderly care reference center in Taguatinga-DF were selected, and information was collected between November 2018 and March 2019. Data collection was initially made by filling in the evaluation form. Subsequently, two questionnaires were administered to caregivers (Clinical Dementia Rating-CDR and Disability Assessment fo...
Source: Revista Brasileira de Cineantropometria e Desempenho Humano - Category: Sports Medicine Source Type: research
Condition:   Stroke Intervention:   Device: T-chair Sponsor:   KU Leuven Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Amyotrophic Lateral Sclerosis;   Brainstem Stroke;   Muscular Dystrophies;   Parkinson's Disease and Parkinsonism;   Multiple System Atrophy;   Brain Tumor Adult;   Spinal Cord Injuries;   Locked-in Syndrome Interventions:   Behavioral: BCI-FIT multi-modal access;   Behavioral: BCI-FIT adaptive signal modeling;   Behavioral: BCI-FIT active querying;   Behavioral: BCI-FIT language modeling Sponsor:   Oregon H...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Stroke;   Subluxation, Glenohumeral Intervention:   Device: kinesiotape Sponsors:   Ankara Physical Medicine and Rehabilitation Education and Research Hospital;   Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Mobility Limitation Interventions:   Behavioral: A 48-hour ROC training program with a standing posture;   Behavioral: A 24-hour ROC training program with a standing posture;   Behavioral: A regular therapy program without receiving any ROC training Sponsor:   Chang Gung Memorial Hospital Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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