Childhood growth and risk of inflammatory bowel disease: a population-based study of 317,030 children.

Conclusion: In this large population-based cohort study, birth weight and childhood growth did not influence risk of IBD, which contrasts with observations in other chronic diseases. Thereby, the study also suggests that pre-clinical effects of adult IBD are not measurable in childhood and that childhood risk factors for IBD do not influence growth. PMID: 31294613 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

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The objective of the study was to (1) characterize and compare the chemical composition at the surface, subsurface and in the bulk of thin plastic films used for portosystemic shunt attenuation in their native state and after plasma exposure. (2) Assess the presence, concentration and location of irritant compounds (e.g dicetyl phosphate) within the films.Attenuated Total Reflectance Infrared Spectroscopy (ATR-IR), X-ray Photoelectron Spectroscopy (XPS) and dynamic Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) were used to analyze thirteen thin plastic films. Sample thickness was visualized and measured using S...
Source: Research in Veterinary Science - Category: Veterinary Research Source Type: research
CONCLUSION: This first randomized resistance training trial in pancreatic cancer patients indicated clinically relevant improve- ments in QoL after 3 but not after 6 months. Given the severity of pancreatic cancer, exercise recommendations may already commence at surgery. PMID: 31431236 [PubMed - in process]
Source: Deutsches Arzteblatt International - Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
Publication date: December 2019Source: Results in Physics, Volume 15Author(s): Abhilash Pathania, Preeti Thakur, Alex V. Trukhanov, Sergei V. Trukhanov, Larissa V. Panina, Ulrike Lüders, Atul ThakurAbstractThis paper reports on the study of series of tungsten doped Ni0.5Zn0.5WxFe2−xO4 (x = 0.0, 0.2, 0.4, 0.6, 0.8, 1.0) ferrites synthesized by a co-precipitation scheme. The crystallite size varies from 62 to 49 nm and the scanning electron microscope (SEM) images show the spinel cubic structure of the powder sample. Energy Dispersive X-ray Fluorescence Spectroscopy (EDXRF) confirms the presence of Ni, Zn, W...
Source: Results in Physics - Category: Physics Source Type: research
In conclusion, the PRPF4 gene plays an important role in the growth of breast cancer cells and is therefore a potential therapeutic target.
Source: Molecular and Cellular Probes - Category: Molecular Biology Source Type: research
Publication date: 15 December 2019Source: Journal of Molecular Structure, Volume 1198Author(s): Lei Wang, Gui-Bin XueAbstractSolvothermal reactions of 1, 3, 5-tris (4-carboxyphenyl)-benzene (H3BTB) with Gd(NO3)·6H2O gave rise to a new highly porous coordination polymer {[Gd(BTB)(H2O)](DMF)(H2O)}n (1) having three dimensional structure. In light of its highly rigid framework as well as the large one-dimensional triangular channel configuration that has abundant open metal sites, we can utilize the resulting activated 1a as effective Lewis catalysts for the acetaldehyde's cyanosilylation at room temperature. The compa...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: 15 December 2019Source: Journal of Molecular Structure, Volume 1198Author(s): Liji John, Arish Dasan, R. Selwin Joseyphus, I. Hubert JoeAbstractCo(II), Ni(II), Cu(II) and Zn(II) complexes of Schiff base ligand (thio-L-his) derived from thiophene-2-carboxaldehyde (thio) with l-histidine (L-his) were synthesised. The thio-L-his and its metal complexes have been optimized and quantum chemical parameters are calculated using density functional theory. Despite several donor sites in the synthesised thio-L-his, the coordination with metal ion occurred through azomethine nitrogen and carboxylate oxygen as eviden...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: Available online 21 August 2019Source: Journal of Molecular LiquidsAuthor(s): Jitendra Kumar Sahoo, Monidipa Konar, Juhi Rath, Devendra Kumar, Harekrushna SahooAbstractThe current investigation reports the removal of Eriochrome Black T (EBT) from aqueous solution by using magnetic hydroxyapatite (M-HAP), a cost-effective adsorbent compared to the other commercial adsorbents. The M-HAP nanocomposite was characterized by Fourier transform infrared (FTIR), X-ray diffraction (XRD), Field emission scanning electron microscope (FE-SEM), Environmental scanning electron (E-SEM), BET surface area analyser, vibrati...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
Publication date: Available online 20 August 2019Source: Journal of Molecular LiquidsAuthor(s): Risa Kawai, Shiho Yada, Tomokazu YoshimuraAbstractQuaternary-ammonium-salt-type amphiphilic compounds ([CnAdA][X], where n represents the alkyl chain length (n = 1, 2, 4, 6, 8, or 10), X represents a counterion such as [BF4]−, [PF6]−, trifluoromethanesulfonate ([OTf]−), bis(fluorosulfonyl)amide ([FSA]−), or bis(trifluoromethanesulfonyl)amide ([NTf2]−), and Ad and A of AdA represent the adamantane structure and quaternary ammonium group, respectively) were synthesized. The melting points of the p...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
Publication date: Available online 20 August 2019Source: Journal of Molecular LiquidsAuthor(s): Sadegh Farhadian, Behzad Shareghi, Farhang Tirgir, Somayeh Reiisi, Neda Gholamian Dehkordi, Lida Momeni, Ehsan HeidariAbstractOver the past decades, anti-cancer drugs consist of cytotoxic drugs have been interested and developed. Despite the great advances in chemotherapy, there is still no certain medical treatment for cancer. During this investigation, a novel 2,5-diketopiperazine derivative 3(R),6(S)-bis (4-hydroxy phenyl)-piperazine-2,5-dione: (BHPPD) was designed, synthesized, and evaluated. The effects on intestinal protea...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
In this study, we performed RNA-sequencing analysis of MCF10A cells and identified 1166 genes that were upregulated and 861 genes that were downregulated by TGF-β. Gene set enrichment analysis revealed that focal adhesion and metabolic pathways were the top enriched pathways of the up- and downregulated genes, respectively. Genes in these pathways also possess significant predictive value for renal cancers. Moreover, we confirmed that TGF-β induced expression of MICAL1 and 2, and the histone demethylase, KDM7A, and revealed their regulatory roles on TGF-β-induced cell migration. We also show a critical effec...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
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