Trends of INR and Fecal Excretion of Vitamin K During Cholestasis Reversal: Implications in the Treatment of Neonates With Intestinal Failure-Associated Liver Disease.

CONCLUSION: Children with IFALD are at risk for vitamin K deficiency during cholestasis reversal. Close monitoring and quantified supplementation of vitamin K may be warranted during this period. However, this should not be guided by INR alone, as it is a poor indicator of vitamin K status. PMID: 31282035 [PubMed - as supplied by publisher]
Source: JPEN Journal Of Parenteral And Enteral Nutrition - Category: Nutrition Authors: Tags: JPEN J Parenter Enteral Nutr Source Type: research

Related Links:

Publication date: Available online 21 September 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Mona Alshahawey, Radwa El borolossy, Lamia El Wakeel, Tamer Elsaid, Nagwa Ali Sabri
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Methylmercury (MeHg), a neurotoxic compound biomagnifying in aquatic food webs, can be a threat to human health via fish consumption. However, the composition and distribution of the microbial communities mediating the methylation of mercury (Hg) to MeHg in marine systems remain largely unknown. In order to fill this knowledge gap, we used the Baltic Sea Reference Metagenome (BARM) dataset to study the abundance and distribution of the genes involved in Hg methylation (the hgcAB gene cluster). We determined the relative abundance of the hgcAB genes and their taxonomic identity in 81 brackish metagenomes that cover spatial,...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
The machinery for mRNA localization is one of crucial molecular structures allowing cellular spatiotemporal organization of protein synthesis. Although the molecular mechanisms underlying mRNA localization have been thoroughly investigated in unicellular organisms, little is known about multicellular and multinuclear filamentous fungi. Here, we conducted single-molecule fluorescence in situ hybridization (smFISH) to first visualize the mRNA molecules of α-amylase, which are encoded by amyB, and which are thought to be abundantly secreted from the hyphal tips of the industrially important fungus Aspergillus oryzae. Co...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
AbstractObjectiveTo evaluate the association between sleep duration and weight gain and incident overweight/obesity in the population of China.MethodsData were derived  from the China Health and Nutrition Survey. Adult participants with baseline data of sleep duration and body mass index (BMI) and who received at least one follow-up evaluation were selected to analyze the association of sleep duration with weight gain (n = 12,871) and incident overweight/obesity  (n = 7,752). Daily sleep duration was categorized into five groups: ≤ 6, 7, 8 (as reference), 9, and ≥ 10 h. The study out...
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
Free 25(OH)D is a stronger predictor of all-cause mortality than total 25(OH)D in older men. Free 1.25(OH)2D, the biologically active metabolite, was not predictive of all-cause mortality.Medscape Medical News
Source: Medscape Diabetes Headlines - Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news
Today's open access paper discusses the impact of mitochondrial DNA damage on female reproductive capabilities. Mitochondria are the power plants of the cell, a herd of hundreds of organelles responsible for packaging the chemical energy store molecule ATP, used to power cellular processes. They are additionally deeply integrated into many core cellular processes. Mitochondria are the evolved descendants of ancient symbiotic bacteria: they carry their own small genome, the mitochondrial DNA, and replicate like bacteria. Unfortunately this mitochondrial DNA is more vulnerable and less proficiently repaired than the nuclear ...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Bacterial infection alongside speed of temperature rise may have triggered mortality, suggests studyHigh temperatures and the persistent warming of oceans have triggered profound changes in marine ecosystems, but a new study suggests that the rate of onset of warming – rather than the peak – could also play a key role in the damage fuelled by climate change.In early July 2017, researchers were drawn to the coast of Eilat, Israel, following sightings of fish carcasses, a rare occurrence in the region ’s coral reefs.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Climate change Oceans Fish Environment World news Science Israel Source Type: news
Authors: MacDonald-Ramos K, Michán L, Martínez-Ibarra A, Cerbón M Abstract Silymarin is obtained from the Milk thistle plant Silybum marianum and has been used over the centuries to treat principally liver disease, although it has also been studied for its beneficial effects in cardioprotection, neuroprotection, immune modulation, and cancer among others. Importantly, silymarin's active component silybin is a flavonolignan that exhibits different activities such as; scavenger, anti-oxidant, anti-inflammatory, and recently revealed, insulin-sensitizing properties which have been explored in clin...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
CONCLUSION: Type 4 collagen could predict the presence of significant and advanced fibrosis in NAFLD patients and it would be a useful tool in routine clinical practice. PMID: 32949785 [PubMed - as supplied by publisher]
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
Vitamin C is one of the safest and most effective nutrients, experts say.
Source: WebMD Health - Category: Consumer Health News Source Type: news
More News: Bilirubin | Children | Cholestasis | Fish | Fish Oil | Liver | Liver Disease | Nutrition | Parenteral Nutrition | Study | Urology & Nephrology | Vitamin K | Vitamin K Deficiency | Vitamins