AMPK ‐SIRT1‐independent inhibition of ANGPTL3 gene expression is a potential lipid‐lowering mechanism of metformin

ConclusionsMetformin inhibits ANGPTL3 expression in the liver in an AMPK ‐SIRT1‐independent manner as a potential mechanism to regulate LPL and lower plasma lipids.

Source: Journal of Pharmacy and Pharmacology - July 4, 2019 Category: Drugs & Pharmacology Authors: Li Lin, Jamie Burke, Sahana Venkatesh, Prabodh Sadana Tags: Research Paper Source Type: research