FDG PET study showing the effect of high altitude and traumatic brain injury on regional glucose uptake in mice

Conclusions: Adaptation of the central nervous system to prolonged hypobaric-hypoxia in C57BL/6 mice varies by brain region (Cramer et al. 2018) and appears to allow the HA-exposed brain more susceptible to repeated concussion relative to sea level mice. Research Support: This work is supported by the Department of Defense through the Center for Neuroscience and Regenerative Medicine and a Uniformed Services University Program Project Grant 308430. Reference: Neuronal and vascular deficits following chronic adaptation to high altitude. Cramer et al. Exp Neurol. 2019 Jan;311:293-304. doi: 10.1016/j.expneurol.2018.10.007. Epub 2018 Oct 13

Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Jaiswal, S., Knutsen, A., Pan, H., Cramer, N., Xu, X., Dardzinski, B., Galdzicki, Z., Allison, N., Haight, T. Tags: Basic Science II (Neurosciences) Source Type: research