Mangiferin Potentiates Neuroprotection by Isoflurane in Neonatal Hypoxic Brain Injury by Reducing Oxidative Stress and Activation of Phosphatidylinositol-3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling.

CONCLUSIONS This study reveals the potent neuroprotective efficacy of mangiferin against HI-induced brain injury via effectively modulating apoptotic pathways, ROS levels, and PI3K/Akt cascades while potentiating protective effects of isoflurane. PMID: 30338764 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30338764?dopt=Abstract

Source: Medical Science Monitor - October 21, 2018 Category: Research Tags: Med Sci Monit Source Type: research