Secondary malignant transformation of testicular teratomas: Case series and literature review

Conclusion The transformation of germ cell tumors to somatic type malignancies is rare. The malignant component can originate from any of the three germ lines. These tumors are resistant to standard chemotherapy for a germ cell tumor and the clinical stage is the most important prognostic factor. At our institution, the malignant component that appeared most frequently was chondrosarcoma.
Source: Actas Urologicas Espanolas - Category: Urology & Nephrology Source Type: research