A behavioral test battery for mouse models of Angelman syndrome: a powerful tool for testing drugs and novel Ube3a mutants

ConclusionsOur study provides a useful tool for preclinical drug testing to identify treatments for Angelman syndrome. Since the phenotypes are observed in several independently derivedUbe3a lines, the test battery can also be employed to investigate the effect of specificUbe3a mutations on these phenotypes.
Source: Molecular Autism - Category: Molecular Biology Source Type: research