IJERPH, Vol. 15, Pages 1679: Rebuilding the Gut Microbiota Ecosystem

IJERPH, Vol. 15, Pages 1679: Rebuilding the Gut Microbiota Ecosystem International Journal of Environmental Research and Public Health doi: 10.3390/ijerph15081679 Authors: Antonella Gagliardi Valentina Totino Fatima Cacciotti Valerio Iebba Bruna Neroni Giulia Bonfiglio Maria Trancassini Claudio Passariello Fabrizio Pantanella Serena Schippa A microbial ecosystem in which bacteria no longer live in a mutualistic association is called dysbiotic. Gut microbiota dysbiosis is a condition related with the pathogenesis of intestinal illnesses (irritable bowel syndrome, celiac disease, and inflammatory bowel disease) and extra-intestinal illnesses (obesity, metabolic disorder, cardiovascular syndrome, allergy, and asthma). Dysbiosis status has been related to various important pathologies, and many therapeutic strategies aimed at restoring the balance of the intestinal ecosystem have been implemented. These strategies include the administration of probiotics, prebiotics, and synbiotics; phage therapy; fecal transplantation; bacterial consortium transplantation; and a still poorly investigated approach based on predatory bacteria. This review discusses the various aspects of these strategies to counteract intestinal dysbiosis.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research