Monocyte/Granulocyte to Lymphocyte ratio and the MELD score as Prognostic Predictors for Early Recurrence of Hepatocellular Carcinoma after Trans-Arterial Chemoembolization.

Monocyte/Granulocyte to Lymphocyte ratio and the MELD score as Prognostic Predictors for Early Recurrence of Hepatocellular Carcinoma after Trans-Arterial Chemoembolization. Br J Biomed Sci. 2018 Jul 11; Authors: Elalfy H, Besheer T, El-Maksoud MA, Farid K, Elegezy M, El Nakib AM, El Aziz MA, El-Khalek AA, El-Morsy A, Elmokadem A, Elsamanoudy AZ, El-Bendary MA Abstract BACKGROUND: The first-line treatment option for intermediate-stage hepatocellular carcinoma is transarterial chemoembolization. Certain blood indices, such as lymphocyte/monocyte ratio (LMR), lymphocyte count, neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), monocyte-granulocyte/lymphocyte ratio (MGLR) and red blood cell distribution width (RDW) are prognostic biomarkers in certain diseases. The model for end-stage liver disease (MELD) and Child-Turcotte-Pugh (CTP) scores have been designed for patients with cirrhosis waiting for liver transplantation and in patients with hepatocellular carcinoma. We hypothesised possible roles for these blood indices, and the clinical MELD and CTP scores as prognostic predictors for early recurrence of hepatocellular carcinoma after transarterial chemoembolization. METHODS: Routine laboratory indices determined the NLR, LMR, MGLR, RDW, PLR, and MELD the CTP scores in 147 patients. Sensitivity and specificity of the indices for hepatocellular carcinoma recurrence 36 months after transarterial chemoembolization were estimated by receiv...
Source: British Journal of Biomedical Science - Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

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