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Zika brain damage may go undetected in pregnancy

(University of Washington Health Sciences/UW Medicine) Zika virus may cause significant damage to the fetal brain even when the baby's head size is normal, according to a primate study. The damage can be difficult to detect even with sophisticated brain scans. It may also occur from infections during childhood and adolescence. Hard hit are brain regions that generate new brain cells. Fetal brain structures that may be injured include those where neural stem cells play a role in learning and memory.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

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This study accessed the patients information on demographic characteristics, physical signs and symptoms. Study population This is a cross-sectional and observational study carried out in Brazil during DENV and ZIKV epidemic occurred in 2016. Patients were assisted at the Healthy Unit UPA Coronel Antonino in Campo Grande, MS, Brazil from February to March of 2016. During the study 134 suspected arboviral infection cases were included and submitted to investigation. Patients presenting fever, rash during acute phase of infection (up to the 7th day after disease onset) followed by at least two of the following signals a...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
This study aimed to assess knowledge of ZIKV among pregnant and inter-conception women and to identify sources of information that might address knowledge gaps. Clients in five federally-funded, bo rder region Healthy Start programs (N = 326) were interviewed in late 2016 about their knowledge of ZIKV prevention methods and whether they believed themselves or their babies to be at risk. Sources of information about ZIKV and demographic characteristics were also measured. Chi square tests i dentified important associations between variables; adjusted odds ratios (AOR) and 95% confidence intervals for knowledge...
Source: Journal of Community Health - Category: International Medicine & Public Health Source Type: research
Authors: Soriano-Arandes A, Rivero-Calle I, Nastouli E, Espiau M, Frick MA, Alarcon A, Martinón-Torres F Abstract INTRODUCTION: Zika virus (ZIKV) infection has caused the most challenging worldwide infectious epidemic outbreak in recent months. ZIKV causes microcephaly and other congenital malformations. There is a need to perform updated systematic reviews on ZIKV infection periodically because this epidemic is bringing up new evidence with extraordinary speed. Areas covered: Evidence related to ZIKV infection in the gestational, perinatal, and early infant periods covering epidemiology, virology, pathogene...
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
The developing fetuses of pregnant women are at high risk of developing serious birth defects following Zika virus infections. We applied an Integrated Vector Control (IVC) approach using source reduction, lar...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research
MONDAY, Feb. 5, 2018 -- Fetal brain damage caused by the Zika virus can go undetected in pregnancy, and can occur even if a baby's head size is normal, research in monkeys suggests. The findings indicate that many children with Zika-related brain...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
by Mauricio A. Salvo, Brock Kingstad-Bakke, Cristhian Salas-Quinchucua, Erwin Camacho, Jorge E. Osorio Mosquito-borne Zika virus (ZIKV) typically causes a mild and self-limiting illness known as Zika fever. Since its recent emergence in 2014 in the American continent, ZIKV infection during pregnancy has been closely associated with a wide range of congenital abnormalities. To date, no vaccines or a ntivirals are publicly available. We developed Zika virus-like particles (VLPs) and evaluated their immunogenicity and protective efficacy in mouse models. ZIKV VLPs (ZIKVLPs) formulated with alum were injected into 6-8-week-ol...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Publication date: 25 March 2018 Source:International Journal of Pharmaceutics, Volume 539, Issues 1–2 Author(s): Melanie Tavares, Márcio Robert Mattos da Silva, Luciana Betzler de Oliveira de Siqueira, Raphaela Aparecida Schuenck Rodrigues, Lolita Bodjolle-d'Almeira, Elisabete Pereira dos Santos, Eduardo Ricci-Júnior The use of natural and synthetic repellents, marketed in different pharmaceutical forms, is growing in the world due to the emerging vector-borne viral diseases as Dengue, Zika, Chikungunya, Yellow Fever and Malaria. The choice of the ideal formulation will depend on a series of factors to...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
One in 10 babies exposed to the Zika virus during pregnancy develop abnormally small heads. A study of twins in Brazil suggests gene activity may decide which
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Study of twins exposed to Zika virus during pregnancy was conducted at the University of S ã o Paulo's Human Genome&Stem Cell Research Centre in Brazil. Results are published in Nature Communications
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
(University of Sao Paulo Scientific Outreach Unit) About 6 percent to 12 percent of the babies born from mothers infected with the Zika virus during pregnancy will have the CZS.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
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