Fibre-rich foods 'may help protect against joint diseases and improve bone health'

People eating adiet featuring plenty of fibre-rich foods such as muesli may experience better bone health and a lower risk of autoimmune diseases. This is according to a new study from Germany's Friedrich-Alexander-Universität Erlangen-Nürnberg, which has shed light on how a healthy diet rich in fibre can alter the behaviour of intestinal bacteria in a way that has a positive impact on chronic inflammatory joint diseases. How does fibre-rich food improve bone health? Published in the journal Nature Communications, the study looked at mice to examine the effect that diet has on the composition of intestinal bacteria, which aid digestion by breaking fibre down into its individual components to be absorbed by the body. It is also known that this process creates short-chain fatty acids that stimulate intestinal movements and deliver an anti-inflammatory effect. This new research indicated that eating more fibre changes intestinal bacteria in such a way that more of these fatty acids are formed in key areas such as the bone marrow, resulting in a reduction in the number of bone-degrading cells. Potential implications As such, sticking to a bacteria-friendly diet could potentially deliver significant anti-inflammatory effects and a positive impact on bone density, hopefully reducing the risk of being affected by painful conditions such as rheumatoidarthritis andosteoporosis. Study leader Dr Mario Zaiss said:"Our findings offer a promising approach for developing ...
Source: Arthritis Research UK - Category: Rheumatology Source Type: news

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In this study, apple fruit (cv. Golden delicious) was used as the materials to study the effects of 0.25, 0.5, 1.0, 2.0 mg/mL trisodium phosphate (TSP) dipping treatment on lesion development of fruit inoculated with A. alternata. In vitro test was conducted to investigate the effect of TSP on mycelia growth of A. alternata. The optimal concentration of TSP was screened to assay its effect on the activity of anti-oxidative enzymes, the content of H2O2 and phenylpropane metabolites in apple fruit. The results showed that the different concentrations of TSP significantly inhibited mycelia growth of A. alternata and indicat...
Source: Physiological and Molecular Plant Pathology - Category: Molecular Biology Source Type: research
Conclusion: We developed a new rapid and efficient method for simultaneous separation of food-borne pathogens. This method eliminates culturing stages and permits the detection and identification of target pathogens in a few hours. PMID: 30873266 [PubMed]
Source: Iranian Journal of Microbiology - Category: Microbiology Tags: Iran J Microbiol Source Type: research
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Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: May 2019Source: Biomedical Signal Processing and Control, Volume 51Author(s): Bing-Hong Lin, Ming-Shaung Ju, Chou-Ching K. LinAbstractA proportional-plus-off control of optogenetic stimulation is implemented using the sample entropy and frequency bands of contralateral depth EEG as the afferent signals for seizure detection and feedback control. The system is tested on mice with mesial temporal epilepsy, induced by lithium-pilocarpine injections. The hippocampus is photic stimulated through an optical fibre inserted using the stereotactic technique, and depth EEG from the hippocampus contralateral to the ...
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
Publication date: June 2019Source: Phytochemistry, Volume 162Author(s): Vijay Joshi, Madhumita Joshi, Diwas Silwal, Kayce Noonan, Sierra Rodriguez, Arianne PenalosaAbstractCitrulline, a non-protein amino acid, is present in large amounts in watermelon (Citrullus lanatus (Thunb.) Matsum. &Nakai Cucurbitaceae) fruits. Amino acid profiling of various tissues of cv. Charleston Gray during plant development confirmed progressive accumulation of citrulline only in the fruit flesh and rind tissues. Citrulline content was positively correlated with precursor (ornithine) and by-product (arginine) amino acids during fruit ripeni...
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Publication date: Available online 15 March 2019Source: Journal of Genetics and GenomicsAuthor(s): Jie Sun, Tao Tao, Wei Zhao, Lisha Wei, Fan She, Pei Wang, Yeqiong Li, Yanyan Zheng, Xin Chen, Wei Wang, Yanning Qiao, Xue-Na Zhang, Min-Sheng ZhuAbstractSeveral factors have been implicated in obesity-related hypertension, but the genesis of the hypertension is largely unknown. We found a significantly upregulated expression of CPI-17 and protein kinase C (PKC) isoforms in the vascular smooth muscles of the high fat diet (HFD)-fed obese mice. The obese wild-type mice showed a significant elevation of blood pressure and enhanc...
Source: Journal of Genetics and Genomics - Category: Genetics & Stem Cells Source Type: research
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Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - Category: Genetics & Stem Cells Source Type: research
Conclusions: We conclude transvaginal estriol potentially offers a suitable physiologic delivery and cost-effective alternative to currently available estrogen regimens in selected patients. Additional studies on mode of delivery, safety, and efficacy merit further investigation.
Source: Menopause - Category: OBGYN Tags: Review Article Source Type: research
D, Džupa V Abstract Celiac disease (gluten-sensitive enteropathy) is currently regarded as a multisystem autoimmune disorder; its clinical signs and symptoms do not involve merely the gastrointestinal tract but are associated with several other medical specialties, including orthopaedics and traumatology. In orthopaedic and trauma patients, celiac disease should be suspected in the following diagnoses: osteomalacia, premenopausal osteoporosis, post-menopausal osteoporosis more severe than expected and refractory to medication, osteoporosis in men under 55 years of age, recurrent bone fractures in the limbs, large...
Source: Acta Orthopaedica - Category: Orthopaedics Authors: Tags: Acta Chir Orthop Traumatol Cech Source Type: research
These patent applications describe and claim inventions related to the protein sFRP-1 and methods of regulating signal transduction pathways using sFRP-1. sFRP-1 is a member of a family of secreted proteins (secreted Frizzled Related Proteins) that were originally identified as being able to bind to Wnt proteins. When bound to Wnts, sFRP-1 alters the ability of Wnt protein to bind its receptor (Frizzled), typically acting as an antagonist of Wnt signaling.More particularly, the patent applications and inventions claimed therein relate to methods for influencing bone remodeling using sFRP-1. In particular, the patent applic...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
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