Resistance to Antibiotics: The Good, the Bad and the Ugly

Antimicrobial drugs play a critical role in the treatment of diseases, their use is essential to protect both human and animal health. However, antimicrobials are often misused for treatment and prevention of diseases in livestock sector, aquaculture as well as crop production. Credit: FAOBy Baher KamalROME, Dec 6 2017 (IPS)The growing resistance to antibiotics and other antimicrobials due to their overuse and misuse both in humans and animals has become an alarming global threat to public health, food safety and security, causing the deaths of 700,000 people each year. This is a fact. The good news is that now more and more countries have adopted measures to prevent the excessive and wrong use of antimicrobials. The bad ones are that these drugs continue to be intensively utilised to accelerate the growth of animals, often for the sake of obtaining greater commercial benefits.According to the first annual survey conducted by the Food and Agriculture Organization of the UN (FAO), the World Health Organization (WHO), and a global intergovernmental body on animal health—the World Organisation for Animal Health (OIE), more than 6.5 billion people – over 90 per cent of the world’s population – now live in country that has in place, or is developing, a national action plan on antimicrobial resistance (AMR).“Nearly all of these plans cover both human and animal health in line with the recommended ‘one health‘ multi-sectoral approach,”...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Editors' Choice Environment Featured Food & Agriculture Global Headlines Health Humanitarian Emergencies IPS UN: Inside the Glasshouse Poverty & SDGs Projects Regional Categories TerraViva United Nations Improving the lives of ru Source Type: news

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CONCLUSION: Prevalence of antibiotic use was high not only versus other hospitals in the region but globally including Africa, coupled with significant evidence of sub-optimal prescribing. Swift action is needed to improve future prescribing to reduce AMR. One or two areas should initially be targeted for quality improvement including development of local guidelines, documentation of antibiotic indications and/or stop/review dates. PMID: 33034234 [PubMed - as supplied by publisher]
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
Publication date: Available online 10 October 2020Source: Journal of Genetics and GenomicsAuthor(s): Chengqi Wang, Justin Gibbons, Swamy R. Adapa, Jenna Oberstaller, Xiangyun Liao, Min Zhang, John H. Adams, Rays H.Y. Jiang
Source: Journal of Genetics and Genomics - Category: Genetics & Stem Cells Source Type: research
Authors: Abdeta D, Kebede N, Giday M, Terefe G, Abay SM Abstract Microbial resistance to the few conventional antitrypanosomal drugs, increasing resistance of vectors to insecticides, lack of effective vaccines, and adverse effects of the existing antitrypanosomal drugs justify the urgent need for effective, tolerable, and affordable drugs. We assessed antitrypanosomal effects of the hydromethanolic extract of Echinops kebericho Mesfin roots against Trypanosoma congolense field isolate using in vitro and in vivo techniques. Parasite load, packed cell volume (PCV), body weight, and rectal temperature in Swiss albino...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
As America ’s biopharmaceutical companies workaround the clock to combat COVID-19, a disease caused by a novel strain of coronavirus, now is an important time to consider how we can prepare for the next public health emergency: Antimicrobial resistance (AMR). AMR occurs when microorganisms such as bacteria, viruses, fungi and parasites change in ways that make the medications used to cure the infections they cause ineffective. According to the Centers for Disease Control and Prevention (CDC), more than 2.8 million antibiotic-resistant infections occur in the U.S. each year, and more than 35,000 people die as a r...
Source: The Catalyst - Category: Pharmaceuticals Tags: Research and Development PhRMA Member Company Infectious Diseases Coronavirus Source Type: news
Raquel Ferrer-Espada1,2, Xiaojing Liu1,2, Xueping Sharon Goh1,2 and Tianhong Dai1,2* 1Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States 2Vaccine &Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States Polymicrobial biofilms, in which mixed microbial species are present, play a significant role in persistent infections. Furthermore, polymicrobial biofilms promote antibiotic resistance by allowing interspecies transfer of antibiotic resistance genes. In the present study, we investigated the effec...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
(CNN) — From climate change to superbugs, the World Health Organization has laid out 10 big threats to our global health in 2019. And unless these threats get addressed, millions of lives will be in jeopardy. Here’s a snapshot of 10 urgent health issues, according to the United Nations’ public health agency: Not vaccinating when you can One of the most controversial recent health topics in the US is now an international concern. “Vaccine hesitancy — the reluctance or refusal to vaccinate despite the availability of vaccines — threatens to reverse progress made in tackling vaccine-prevent...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN Local TV Source Type: news
Author Affiliations open 1Public Health Institute, Oakland, California, USA 2Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA 3Instituto de Microbiologia, Colegio de Ciencias Biologicas y Ambientales, Universidad San Francisco de Quito, Quito, Ecuador 4Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan, USA 5Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA 6Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, Minnesota, USA PDF Version (176 KB) Abstract ...
Source: EHP Research - Category: Environmental Health Authors: Tags: Brief Communication Source Type: research
Posters: Misuse of antibiotics and risks. Credit: WHOBy Baher KamalROME, Oct 4 2017 (IPS)The world is running out of new antibiotics to combat the growing threat of antimicrobial resistance, a new specialised report warns ahead of this year’s World Antibiotic Awareness Week, adding that most of the drugs currently in the clinical pipeline are modifications of existing classes of antibiotics and are only short-term solutions. The latest World Health Organization (WHO) report on this issue “Antibacterial agents in clinical development – an analysis of the antibacterial clinical development pipeline, includi...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Featured Global Headlines Health Human Rights TerraViva United Nations Source Type: news
Since the introduction of penicillin in the middle of the 20th century, antimicrobial treatments have been used not only in human medicine but in veterinary care as well. But their excessive use in livestock (and aquaculture) contaminates the environment and contributes to a rise of resistant microorganisms, posing threats to human health, animal health, food security and people’s livelihoods. Photo: FAOBy Baher KamalROME, Jan 11 2017 (IPS)There is a major though silent global threat to human and animal health, with implications for both food safety and food security and the economic well-being of millions of farming...
Source: IPS Inter Press Service - Health - Category: Global & Universal Authors: Tags: Featured Food & Agriculture Global Headlines Health Human Rights Projects TerraViva United Nations Improving the lives of rural populations: better nutrition & agriculture productivity Source Type: news
By Kate Kelland LONDON, April 29 (Reuters) - Only 34 countries have national plans to fight the global threat of antibiotic resistance, meaning few are prepared to tackle "superbug" infections which put even basic healthcare at risk, the WHO said on Wednesday. In a survey of government plans to tackle the issue, the World Health Organization said only a quarter of the 133 countries that responded were addressing the problem. "This is the single greatest challenge in infectious diseases today," said Keiji Fukuda, the WHO's assistant director-general for health security. "All typ...
Source: Science - The Huffington Post - Category: Science Source Type: news
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