Pramipexole Overdose Associated with Visual Hallucinations, Agitation and Myoclonus.

DISCUSSION: Pramipexole overdose with hallucination, agitation, and myoclonus is consistent with adverse effects reported with therapeutic toxicity, but mirtazapine and venlafaxine may have contributed. Pramipexole concentrations exceeded the therapeutic range for over 24 h. With the increasing use of pramipexole in restless legs syndrome, adult overdoses may become more common. PMID: 28547577 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28547577?dopt=Abstract

Source: Journal of Medical Toxicology - May 25, 2017 Category: Toxicology Authors: Cardon-Dunbar A, Robertson T, Roberts MS, Isbister GK Tags: J Med Toxicol Source Type: research