Insights into the molecular mechanisms of Polygonum multiflorum Thunb-induced liver injury: a computational systems toxicology approach.

In conclusion, this computational systems toxicology method reveals possible toxic components and could be very helpful for understanding the mechanisms of HILI. In this way, the method might also facilitate the identification of novel hepatotoxic herbs.
PMID: 28239160 [PubMed - as supplied by publisher]

Source: Acta Pharmacologica Sinica - February 26, 2017 Category: Drugs & Pharmacology Authors: Wang YY, Li J, Wu ZR, Zhang B, Yang HB, Wang Q, Cai YC, Liu GX, Li WH, Tang Y Tags: Acta Pharmacol Sin Source Type: research