Systemic corticosteroid regimens for prevention of bronchopulmonary dysplasia in preterm infants.

CONCLUSIONS: Despite the fact that some studies reported a modulating effect of treatment regimens in favor of higher-dosage regimens on the incidence of BPD and neurodevelopmental impairment, recommendations on the optimal type of corticosteroid, the optimal dosage, or the optimal timing of initiation for the prevention of BPD in preterm infants cannot be made based on current level of evidence. A well-designed large RCT is urgently needed to establish the optimal systemic postnatal corticosteroid dosage regimen. PMID: 28141913 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/28141913?dopt=Abstract

Source: Cochrane Database of Systematic Reviews - January 30, 2017 Category: Journals (General) Authors: Onland W, De Jaegere AP, Offringa M, van Kaam A Tags: Cochrane Database Syst Rev Source Type: research