A modular, prospective, semi‐automated drug safety monitoring system for use in a distributed data environment

ConclusionsBeta‐testing across nine drug‐outcome examples demonstrated the feasibility of the proposed semi‐automated prospective monitoring approach. In retrospective assessments, the system identified an increased risk of myocardial infarction with rofecoxib and an increased risk of rhabdomyolysis with cerivastatin years before these drugs were withdrawn from the market. Copyright © 2014 John Wiley & Sons, Ltd.

Source: Pharmacoepidemiology and Drug Safety - April 30, 2014 Category: Drugs & Pharmacology Authors: Joshua J. Gagne, Shirley V. Wang, Jeremy A. Rassen, Sebastian Schneeweiss Tags: Original Report Source Type: research