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Zydus Pharma recalls 44.8 K bottles of antidepressant in US
The reason for recall is presence of foreign tablets. "Risperidone tablets were found in bottle of paroxetine tablets", the report said. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - September 21, 2017 Category: Pharmaceuticals Source Type: news

A Suicide Leaves Grief and Tough Questions About an Antidepressant
Some patients taking antidepressants experience nearly intolerable agitation, a side effect that experts say may be linked to suicide. (Source: NYT Health)
Source: NYT Health - September 11, 2017 Category: Consumer Health News Authors: RONI CARYN RABIN Tags: Depression (Mental) Anxiety and Stress Drugs (Pharmaceuticals) Suicides and Suicide Attempts Antidepressants Mental Health and Disorders Labeling and Labels (Product) Paxil (Drug) Suits and Litigation (Civil) Psychiatry and Psychiatrists Source Type: news

Lawsuit Over a Suicide Points to a Risk of Antidepressants
Some patients taking antidepressants experience nearly intolerable agitation, a side effect that experts say may be linked to suicide. (Source: NYT Health)
Source: NYT Health - September 11, 2017 Category: Consumer Health News Authors: RONI CARYN RABIN Tags: Depression (Mental) Anxiety and Stress Drugs (Pharmaceuticals) Suicides and Suicide Attempts Antidepressants Mental Health and Disorders Labeling and Labels (Product) Paxil (Drug) Suits and Litigation (Civil) Psychiatry and Psychiatrists Source Type: news

Lupin recalls 12,480 bottles of anti-depressant drug from US
Lupin Pharmaceuticals Inc is recalling 12,480 bottles of Paroxetine extended-release tablets in the strength of 12.5 mg manufactured by Lupin Ltd. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 19, 2017 Category: Pharmaceuticals Source Type: news

Label Or Liability: GSK Faces $3M Verdict Over Product It Didn't Make
This spring, a Chicago federal jury awarded $3 million to the widow of a lawyer who committed suicide by stepping in front of a CTA L train in Chicago ’s Loop in 2010 shortly after taking a generic version of the antidepressant drug Paxil. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 12, 2017 Category: Pharmaceuticals Authors: Legal Newsline, Contributor Source Type: news

GSK must pay $3 million in generic Paxil suicide lawsuit: U.S. jury
(Reuters) - GlaxoSmithKline must pay $3 million to a woman who sued the drug company over the death of her husband, a lawyer who committed suicide after taking a generic version of the antidepressant Paxil, a U.S. jury said on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - April 20, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Not Just for Attention: Stop Teen Suicide
The subject of depression and suicide, especially in the case of children and teens, is a tremendous concern. Unfortunately, many cases go missed not necessarily because those surrounding these young people don’t care or pay enough attention to them, but more because they aren’t aware of what to look out for. I am a suicide survivor. I also grew up with a suicidal mother and witnessed a peer successfully commit suicide, ironically, when I was in the emergency room beside her being treated for the same thing. I was saved, while her family still mourns for her. These experiences, including the fact that my twelve...
Source: Psych Central - March 29, 2017 Category: Psychiatry Authors: Chynna Laird Tags: Antidepressants Children and Teens Depression Medications Personal Stories Self-Esteem Stress Suicide Therapists Spill Treatment Anxiety Coping Skills Depression Mood Depressive Episode Major Depressive Disorder Monoamine Oxi Source Type: news

NeuroBreak: Opioid Scripts Down at the VA; Paxil on Trial
(MedPage Today) -- News and commentary from the world of neurology and neuroscience (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - March 14, 2017 Category: Geriatrics Source Type: news

Lupin launches generic anti-depression drug in US
The company "announced the launch of generic paxil CR extended release tablets, 12.5 mg, 25 mg and 37.5 mg, having received an approval from the USFDA earlier (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 7, 2017 Category: Pharmaceuticals Source Type: news

Paxil (Paroxetine Hydrochloride) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news

Paxil-CR (Paroxetine Hydrochloride) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news

Brisdelle (Paroxetine Capsules 7.5 mg) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news

Pexeva (Paroxetine Mesylate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 15, 2016 Category: Drugs & Pharmacology Source Type: news

Falsified drug studies led to millions of children receiving dangerous antidepressants
(NaturalNews) In 2001, the pharmaceutical company SmithKline Beecham (now GlaxoSmithKline) published a trial known as Study 329, which claimed that the drug paroxetine – known as Paxil or Seroxat – was "generally well tolerated" and that it helped cure depression in children... (Source: NaturalNews.com)
Source: NaturalNews.com - August 30, 2016 Category: Consumer Health News Source Type: news

3 Drugs with the Most Severe Side Effects
Image Source Drugs have been known to have some sort of side effects on patients. Most of them are not often discussed in the health tabloids. While other drugs have side effects that are very nominal when compared to the benefits the patient derives from their usage, others have side effects that can impact the lives of their users forever. The most common side effects people experience from drug usage are gastrointestinal related issues which include constipation, nausea, and vomiting. Some other drugs can leave you feeling tired and dizzy for a short period of time. Combining these drugs with simple aspirin will usuall...
Source: Healthy Living - The Huffington Post - August 19, 2016 Category: Consumer Health News Source Type: news

Comparative risk of hip fractures in elderly nursing home patients with depression using paroxetine and other selective serotonin reuptake inhibitors - Bali V, Chatterjee S, Johnson ML, Chen H, Carnahan RM, Aparasu RR.
AIM: To evaluate comparative safety of paroxetine and other selective serotonin reuptake inhibitors (SSRIs) for the risk of hip fractures. Patients & methods: A propensity score-matched retrospective cohort study was conducted using 2007-2010 Minimum Data ... (Source: SafetyLit)
Source: SafetyLit - July 28, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Study Defends Antidepressant Use In Pregnancy Despite Birth Defect Risks
While SSRI antidepressants are arguably still the most consumed drug class in the US, sales peaked in 2008 and have declined by four percent every year since, according to Research and Markets. There are many reasons for declining SSRI sales from unwanted side effects like weight gain and sexual dysfunction to "Prozac Poop-out" in which patients develop tolerance and the pills quit working. Still, a major reason for declining sales are SSRI's strong links to suicide and birth defects. In 2004, the FDA added "Black Box" warnings to SRRIs, highlighting suicide risks and the need for close monitoring of...
Source: Healthy Living - The Huffington Post - July 26, 2016 Category: Consumer Health News Source Type: news

Both paroxetine and impramine appear to be ineffective in adolescents with major depression, furthermore doubts have risen about their safety
Adolescents suffering from major depression often receive treatment with antidepressants. However the evidence for the efficacy of both newer antidepressants and tricyclic antidepressants in major depression in adolescence is very limited. Systematic reviews1 found a statistically significant difference in efficacy in favour of antidepressants versus placebo, which was not clinically relevant. However, they concluded that the large majority of studies on this topic shows serious methodological flaws, selecting patients with advertisements, excluding patients with suicide r...
Source: Current Awareness Service for Health (CASH) - July 12, 2016 Category: Consumer Health News Source Type: news

paroxetine (Brisdelle)
Title: paroxetine (Brisdelle)Category: MedicationsCreated: 2/24/2015 12:00:00 AMLast Editorial Review: 7/8/2016 12:00:00 AM (Source: MedicineNet Menopause General)
Source: MedicineNet Menopause General - July 8, 2016 Category: Primary Care Source Type: news

Fentanyl can cause serotonin syndrome
3.5 out of 5 stars Serotonin Syndrome Induced by Fentanyl in a Child: Case Report. Robles LA. Clin Neuropharmacol 2015 Sept-Oct;38:206-8. Abstract When many clinicians think of serotonin syndrome (SS), they consider the usual suspects: Selective Serotonin Uptake Inhibitors (SSRIs) Citalopram Fluoxetine Sertraline Escitalopram Paroxetine Serotonin-Norepinephrine Reuptake Inhibitors Venlafaxine Duloxetine Antidepressants Trazodone Buspirone Clomipramine Aside from these common culprits, there are other commonly used drugs whose clear association with serotonin syndrome is less-often realized: Fentanyl ...
Source: The Poison Review - July 8, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical fentanyl opioid serotonin syndrome Source Type: news

Depression blood test could lead to personalised treatments
Conclusion This study shows how a new blood test in development can help identify people with depression who are most and least likely to benefit from antidepressants. While promising, the test is far from perfect. For example, it missed 39-43% of non-responders, meaning these people would continue to receive standard antidepressant treatment that is unlikely to work for them. A large proportion of patients (22-38%) also fell into the "intermediate" group who were neither responders nor non-responders, so the test wasn't too useful here. This means there is a significant proportion of people with...
Source: NHS News Feed - June 7, 2016 Category: Consumer Health News Tags: Mental health Medication Source Type: news

Antidepressants linked to premature births
(NaturalNews) Even though studies have already linked SSRI use during pregnancy to birth defects and autism in children, the pills are continually and dangerously prescribed to pregnant women. Common SSRIs like Prozac, Paxil and Zoloft artificially increase serotonin levels in the... (Source: NaturalNews.com)
Source: NaturalNews.com - May 28, 2016 Category: Consumer Health News Source Type: news

If you use Benadryl, Paxil, Dramamine it's REALLY time to stop: definite links to dementia, cognitive damage found with these OTC allergy drugs
(NaturalNews) Over-the-counter drugs, many of them formerly only available by prescription, are in abundance, and they supposedly treat a wide range of conditions and minor illnesses. But new research shows that many of these come with a host of side effects and potential side effects... (Source: NaturalNews.com)
Source: NaturalNews.com - April 29, 2016 Category: Consumer Health News Source Type: news

Researchers visualize brain's serotonin pump, provide blueprint for new, more effective SSRIs
Researchers have uncovered remarkably detailed 3-D views of one of the most important transporters in the brain -- the serotonin transporter. Their study provides fresh insight into how citalopram and paroxetine, two of the most widely prescribed selective serotonin reuptake inhibitors, or SSRIs, interact with and inhibit serotonin transport. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 6, 2016 Category: Science Source Type: news

Researchers visualize brain's serotonin pump, provide blueprint for new, more effective SSRIs
(Oregon Health & Science University) Researchers at Oregon Health & Science University's Vollum Institute have uncovered remarkably detailed 3-D views of one of the most important transporters in the brain -- the serotonin transporter. Their study, published online today in the journal Nature, provides fresh insight into how citalopram and paroxetine, two of the most widely prescribed selective serotonin reuptake inhibitors, or SSRIs, interact with and inhibit serotonin transport. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 6, 2016 Category: Biology Source Type: news

Should Paxil be banned? The only 'evidence' of effectiveness was ghostwritten by Glaxo Smith Kline's public relations firm
(NaturalNews) In 2001, a study was published in the Journal of the American Academy of Child and Adolescent Psychiatry, showing that the SSRI antidepressant paroxetine – sold under the names Paxil, Aropax and Seroxat – was safe, well tolerated and effective for the treatment... (Source: NaturalNews.com)
Source: NaturalNews.com - March 29, 2016 Category: Consumer Health News Source Type: news

Treatment for Seasonal Affective Disorder
Seasonal affective disorder(SAD) — also known as the winter blues or winter depression — is a seasonal but serious disorder that impacts many people with the changing of the seasons (from fall into winter, or from spring into summer). Luckily there are a number of effective treatment options for anyone who is suffering from seasonal affective disorder. Light Boxes Research has found that the majority of those suffering from the winter blues experienced relief solely from the regular use of light boxes. Light boxes emit high intensities of light of 2,500 to 10,000 lux (as compared to a normal light fixture that ...
Source: Psych Central - March 11, 2016 Category: Psychiatry Authors: John M. Grohol, Psy.D. Tags: Antidepressants Depression Disorders Medications Psychotherapy Seasonal Affective Disorder Treatment help for the winter blues help for winter depression seasonal affective disorder treatment treatment for sad treatment for seasonal Source Type: news

Comorbid tics have no effect on response to cognitive-behavioural therapy in youth with obsessive-compulsive disorder
Tic-related obsessive-compulsive disorder (OCD) is a DSM-5 diagnostic subtype that is estimated to occur in 10–40% of cases with childhood onset.1 Studies comparing tic-related and non-tic-related OCD have found consistent differences in sex, onset age, comorbidity and course, but inconsistent differences in OCD symptoms and prevalence of OCD and tics in first-degree relatives.1 ,2 Medication trials have indicated that tic-related OCD is less responsive to sertraline, fluvoxamine and paroxetine; however, tic history appears to have no effect on the response of OCD in youth to either ...
Source: Current Awareness Service for Health (CASH) - March 4, 2016 Category: Consumer Health News Source Type: news

Antidepressant may improve cognitive symptoms in people with HIV
The antidepressant paroxetine modestly improves decision-making and reaction time, and suppresses inflammation in people with HIV-associated cognitive impairment, physicians report at the conclusion of a small, placebo-controlled clinical trial. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 25, 2016 Category: Science Source Type: news

Antidepressant may improve cognitive symptoms in people with HIV
(Johns Hopkins Medicine) In a small, placebo-controlled clinical trial, Johns Hopkins physicians report that the antidepressant paroxetine modestly improves decision-making and reaction time, and suppresses inflammation in people with HIV-associated cognitive impairment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 25, 2016 Category: Global & Universal Source Type: news

How Can Paxil Help Generalized Anxiety Disorder?
Paxil (paroxetine) is an antidepressant medication in the same class as Prozac and Zoloft. It is also used to treat generalized anxiety disorder. (Source: About.com Mental Health)
Source: About.com Mental Health - February 17, 2016 Category: Psychiatry Tags: health Source Type: news

What Are Current Treatments for Postpartum Depression?
Discussion Postpartum depression affects 10 to 20% of women after delivery, but less than half of these women are detected. Postpartum depression is defined as major depressive episodes with symptom onset during pregnancy or in the first four weeks following delivery. There is recognition that symptoms may begin later after delivery but the mother would not be diagnosed with PPD. PPD is distinct from postpartum blues which occur in 50 to 80% of new mothers. They occur within 1 to 2 days of delivery and resolve within 10-14 days of delivery. Symptoms include anxiety, depression, irritability, tearfulness, poor sleep, and a...
Source: PediatricEducation.org - February 15, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Antidepressants linked to suicide and aggression in teens
ConclusionPerhaps the most troubling aspect of this paper is not the increased risk of suicidal thoughts in young people, as that has been known for many years. What is worrying is the researchers’ conclusion that they are unable to tell the true extent of harms from antidepressants, because of poor data collection and availability.RCTs are designed to test the effects of treatments with as little bias as possible. However, if the right data on adverse effects is not collected in the trials, or is not made public, we cannot balance the benefits and risks of treatment in a fair and transparent way. According to the da...
Source: NHS News Feed - January 28, 2016 Category: Consumer Health News Tags: Mental health Medication Source Type: news

Anti-depressants for teens: A second look
This study highlights the importance of talking to your trusted doctor about the things you hear before just accepting the version of results presented to you. As a doctor, I look forward to more studies that re-examine our current understanding of research data. I hope they will help provide the important information I need to best guide my patients. Related Post:Teen suicide tries increased after FDA toughened…Teens with upbeat friends may have better emotional healthAntidepressants cause minimal weight gainThe placebo effect: Amazing and realHeads up, parents: New study with important information…The post ...
Source: New Harvard Health Information - January 22, 2016 Category: Consumer Health News Authors: Nandini Mani, MD Tags: Anxiety and Depression Behavioral Health Children's Health Parenting antidepressants teens Source Type: news

GSK to Face First Trial Over Adult Paxil Suicide
A U.S. District Judge declined to rule on a pair of motions filed by GSK defense lawyers, meaning the drugmaker will head to court to face claims that a generic version of its Paxil antidepressant caused an Illinois man's suicide. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - January 15, 2016 Category: Pharmaceuticals Source Type: news

Widely Prescribed Antidepressant Linked to Birth DefectsWidely Prescribed Antidepressant Linked to Birth Defects
Use of the selective serotonin reuptake inhibitor paroxetine during pregnancy may increase the risk of congenital and cardiac malformations in children, new research shows. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 14, 2016 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Paroxetine in early pregnancy once again linked to birth defects
(Reuters Health) - Women who take the antidepressant paroxetine (Paxil, Seroxat) early in pregnancy may be more likely to have babies with birth defects, a review of previous research suggests. (Source: Reuters: Health)
Source: Reuters: Health - January 13, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

Paroxetine Use in First Trimester Linked to Infant Heart Defects (CME/CE)
(MedPage Today) -- Meta-analysis shows increased risk of congenital, cardiac anomalies (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - January 7, 2016 Category: OBGYN Source Type: news

Antidepressant paroxetine use linked to risk of birth defects
ConclusionThe big question for pregnant women with any type of illness is always whether the benefits of treatment will outweigh any possible risk of harm to their babies. The question of whether paroxetine can cause birth defects has been under discussion since 2005, when a small study suggested an increased risk of heart malformations. Since then, there have been many studies with conflicting results. This systematic review brings together the latest research and pools the results to come up with a best estimate of the risk of birth defects linked to paroxetine. The strengths of the study are that it was a systematic rev...
Source: NHS News Feed - January 6, 2016 Category: Consumer Health News Tags: Medication Pregnancy/child Source Type: news

Take Antidepressants? You May Be Staving Off Dementia
When you take an SSRI or mood stabilizer, you encounter plenty of people who say they, too, think they could benefit from something like that but they never would because we don't yet know what the end results could be. What if, in old age, they ended up growing a third arm because of their decades of Prozac? (Okay, no one's ever said that to me, but there are so many ignorant people running around telling those who take such medications they are not sober that I wouldn't put it past them. Ahem. Different topic.) Point being: As someone who's taken various medications of this ilk over the years, I've wrestled with the noti...
Source: Healthy Living - The Huffington Post - December 15, 2015 Category: Consumer Health News Source Type: news

Talking therapy 'as effective as antidepressants' study finds
ConclusionPrevious research has shown that both second generation antidepressants and CBT can be helpful for people with depression. This study found that they seem to work about as well as each other.The study has many strengths, including the fact it is a systematic review, and includes information from RCTs involving more than 1,500 people. However, the studies don't give us much information about adverse effects of treatments, or who responds best to which type of treatment. This is important, because what works for one person may not work as well for another. Some doctors think people with severe depression need to be...
Source: NHS News Feed - December 10, 2015 Category: Consumer Health News Tags: Mental health Medical practice Source Type: news

Jubilant Life gets USFDA nod for generic anti-depressant tablets
The final approval for abbreviated new drug application for Paroxetine tablets of Apotex is for strengths of 10 mg, 20 mg, 30 mg and 40 mg, the company said. (Source: The Economic Times)
Source: The Economic Times - December 1, 2015 Category: Consumer Health News Source Type: news

[Podcast] Science Signaling Podcast for 24 November 2015: Antidepressants and epigenetics
The antidepressant paroxetine affects epigenetic regulation of Bdnf. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - November 25, 2015 Category: Science Authors: Theo Rein and Annalisa M. VanHook Source Type: news

[Research Article] Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine
Chaperone switching at the kinase CDK5mediates epigenetic effects of antidepressants. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - November 23, 2015 Category: Science Authors: Nils C. Gassen, Gabriel R. Fries, Anthony S. Zannas, Jakob Hartmann, J├╝rgen Zschocke, Kathrin Hafner, Tania Carrillo-Roa, Jessica Steinbacher, S. Nicole Prei├činger, Lianne Hoeijmakers, Matthias Knop, Frank Weber, Stefan Kloiber, Susanne Lucae, George P. Source Type: news

Scientific fraud uncovered in antidepressant study that claims psych drugs are safe for children
(NaturalNews) A landmark study which concluded that antidepressant drug Paxil (paroxetine) was safe for use among teenagers was fraudulent, suggests a reanalysis of the previously recorded data.The original study, published in the British Medical Journal (BMJ) in 2001, claimed... (Source: NaturalNews.com)
Source: NaturalNews.com - November 4, 2015 Category: Consumer Health News Source Type: news

Big Pharma published fraudulent study to sell deadly psych drugs to young children
(NaturalNews) Shocking information has surfaced that once again reinforces Big Pharma's greed and do-anything-to-sell approaches. After a review of pharma giant SmithKline Beecham's (now GlaxoSmithKline) popular 2001 study that touted the adolescent antidepressant Paxil as effective... (Source: NaturalNews.com)
Source: NaturalNews.com - October 27, 2015 Category: Consumer Health News Source Type: news

Paroxetine in postmortem fluids and tissues from nine aviation accident victims - Lewis RJ, Kemp PM, Johnson RD.
Paroxetine is a selective serotonin reuptake inhibitor commonly prescribed for the treatment of depression, obsessive-compulsive disorder, panic disorder, social anxiety disorder and post-traumatic stress disorder. While the use of paroxetine is considered... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - October 6, 2015 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Rehash of 2001 Study Finds Paroxetine, Imipramine Ineffective, Unsafe for Teens
Both paroxetine and imipramine are ineffective and unsafe for treating adolescents with depression, according to a reanalysis of a 2001 study that was recently published online. (Source: AAFP News)
Source: AAFP News - September 30, 2015 Category: Primary Care Source Type: news

Science worshippers claim science "corrects itself", but this fraudulent study on antidepressants proves that scientific fraud lingers for decades with no correction
(NaturalNews) In 2001, a study was published that had many people singing the praises of an adolescent antidepressant chemically known as Paroxetine. Since then, it's been sold in the UK as Seroxat and in the US as Paxil. That study, which was published in the Journal of the American... (Source: NaturalNews.com)
Source: NaturalNews.com - September 29, 2015 Category: Consumer Health News Source Type: news