A shared effect of paroxetine treatment on gray matter volume in depressive patients with and without childhood maltreatment: a voxel-based morphometry study - Lu XW, Guo H, Sun JR, Dong QL, Zhao FT, Liao XH, Zhang L, Zhang Y, Li WH, Li ZX, Liu TB, He Y, Xia MR, Li LJ.
This study assessed whether antidepressant drug treatment has a common effect on gray matter (GM) volume in MDD patients with and without childhood maltreatment (CM). METHODS: T1-weighted structural magnetic resonance imaging data were collec... (Source: SafetyLit)
Source: SafetyLit - October 5, 2018 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Medical News Today: What is paroxetine?
Paroxetine oral tablets are used to treat mood and anxiety disorders. This prescription medication is available in immediate-release and extended-release forms. It ’s also available as both a generic drug and as the brand-name drugs Paxil, Paxil CR, and Pexeva. Learn about side effects, dosage, warnings, and more. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 27, 2018 Category: Consumer Health News Tags: Pharmacy / Pharmacist Source Type: news

U.S. appeals court says GSK cannot be sued over generic drug suicide
A U.S. appeals court on Wednesday tossed a $3 million verdict against GlaxoSmithKline over the suicide of an attorney who took a generic version of the company's antidepressant Paxil, finding the company could not be held liable for injuries allegedly caused by a generic copy. (Source: Reuters: Health)
Source: Reuters: Health - August 22, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Morning Break: Ebola Blows Up in Congo; $3,769 Screw; I Love You, Paxil
(MedPage Today) -- Health news and commentary from around the Web gathered by the MedPage Today staff (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - May 14, 2018 Category: Psychiatry Source Type: news

Some antidepressants linked to dementia risk
Scientists say doctors should consider weaning patients with depression, Parkinsons or bladder problems off anticholinergic drugsSome antidepressants and bladder medicines could be linked to dementia, according to a team of scientists who are calling for doctors to think about “de-prescribing” them where possible.Tricyclic antidepressants such as amitriptyline, which are also prescribed for pain and to help with sleeping, and one of the SSRI class, paroxetine (also known as Seroxat), are implicated by the largest ever study to look at this possible risk.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - April 25, 2018 Category: Science Authors: Sarah Boseley Health editor Tags: Dementia Mental health Medical research Science University of East Anglia Depression Parkinson's disease Source Type: news

Many People Taking Antidepressants Discover They Cannot Quit
Long-term use of the medications is surging in the United States, according to an analysis by The Times. One reason: withdrawal symptoms that make it difficult to stop. (Source: NYT Health)
Source: NYT Health - April 7, 2018 Category: Consumer Health News Authors: BENEDICT CAREY and ROBERT GEBELOFF Tags: Depression (Mental) Drugs (Pharmaceuticals) Mental Health and Disorders Antidepressants Psychiatry and Psychiatrists Addiction (Psychology) Prozac (Drug) Cymbalta (Drug) Paxil (Drug) Zoloft (Drug) Eli Lilly and Company Food and Drug Source Type: news

Lexapro vs. Paxil
Title: Lexapro vs. PaxilCategory: MedicationsCreated: 2/26/2018 12:00:00 AMLast Editorial Review: 2/26/2018 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - February 26, 2018 Category: Psychiatry Source Type: news

These Antidepressants Are Most Effective, Study Says
Millions of people take antidepressants for depression. But there’s long been debate over just how effective the medications actually are. On Wednesday, a large new study provides evidence that antidepressants are more effective than placebo at treating acute depression in adults. The study, published in the journal The Lancet, looked at the published data from 522 randomized controlled trials testing 21 different types of antidepressants. The study authors also reached out to pharmaceutical companies and study authors for additional unpublished study data. All told, the data collection included 116,477 men and women...
Source: TIME: Health - February 21, 2018 Category: Consumer Health News Authors: Alexandra Sifferlin Tags: Uncategorized healthytime Mental Health/Psychology Source Type: news

Lupin, Cadila recall drugs in US Market
Zydus Pharmaceuticals USA Inc, arm of Cadila Healthcare, is also recalling 19,812 bottles of Paroxetine tablets in the strength of 30 mg from the US market. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 7, 2017 Category: Pharmaceuticals Source Type: news

Lupin, Cadila Healthcare recall drugs in US
Zydus Pharmaceuticals USA Inc, arm of Cadila Healthcare, is also recalling 19,812 bottles of Paroxetine tablets in the strength of 30 mg from the US market. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 7, 2017 Category: Pharmaceuticals Source Type: news

Low-dose Paroxetine for Pruritus in a Palliative Care Patient Low-dose Paroxetine for Pruritus in a Palliative Care Patient
Pruritus is a distressing symptom commonly seen in cancer patients in palliative care. Might paroxetine be an effective treatment?Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 23, 2017 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Exploring the History & Treatment of PTSD: An Interview with Dr. Paula P. Schnurr
As we celebrate Veterans Day (and Remembrance Day in Canada) and honoring military veterans, many of us think back to World War I but also many other wars throughout history. I recalled the 1980s, when Iran was engaged in an almost decade-long war with Iraq, and millions were killed or injured on both sides. In the West, the older generations may recall World War II and the Vietnam War, while the younger ones remember the more recent wars in Iraq and Afghanistan. We think of the millions who have fought, who have come back with injuries, and those who died serving their countries. But the numbers we rarely think about: How...
Source: Psych Central - November 11, 2017 Category: Psychiatry Authors: Arash Emamzadeh Tags: Interview Medications PTSD Trauma Treatment Combat Trauma Posttraumatic Stress Disorder PSTD Traumatic Experiences veterans Veterans day Source Type: news

Zydus Pharma recalls 44.8 K bottles of antidepressant in US
The reason for recall is presence of foreign tablets. "Risperidone tablets were found in bottle of paroxetine tablets", the report said. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - September 21, 2017 Category: Pharmaceuticals Source Type: news

A Suicide Leaves Grief and Tough Questions About an Antidepressant
Some patients taking antidepressants experience nearly intolerable agitation, a side effect that experts say may be linked to suicide. (Source: NYT Health)
Source: NYT Health - September 11, 2017 Category: Consumer Health News Authors: RONI CARYN RABIN Tags: Depression (Mental) Anxiety and Stress Drugs (Pharmaceuticals) Suicides and Suicide Attempts Antidepressants Mental Health and Disorders Labeling and Labels (Product) Paxil (Drug) Suits and Litigation (Civil) Psychiatry and Psychiatrists Source Type: news

Lawsuit Over a Suicide Points to a Risk of Antidepressants
Some patients taking antidepressants experience nearly intolerable agitation, a side effect that experts say may be linked to suicide. (Source: NYT Health)
Source: NYT Health - September 11, 2017 Category: Consumer Health News Authors: RONI CARYN RABIN Tags: Depression (Mental) Anxiety and Stress Drugs (Pharmaceuticals) Suicides and Suicide Attempts Antidepressants Mental Health and Disorders Labeling and Labels (Product) Paxil (Drug) Suits and Litigation (Civil) Psychiatry and Psychiatrists Source Type: news

Lupin recalls 12,480 bottles of anti-depressant drug from US
Lupin Pharmaceuticals Inc is recalling 12,480 bottles of Paroxetine extended-release tablets in the strength of 12.5 mg manufactured by Lupin Ltd. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - July 19, 2017 Category: Pharmaceuticals Source Type: news

Label Or Liability: GSK Faces $3M Verdict Over Product It Didn't Make
This spring, a Chicago federal jury awarded $3 million to the widow of a lawyer who committed suicide by stepping in front of a CTA L train in Chicago ’s Loop in 2010 shortly after taking a generic version of the antidepressant drug Paxil. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 12, 2017 Category: Pharmaceuticals Authors: Legal Newsline, Contributor Source Type: news

GSK must pay $3 million in generic Paxil suicide lawsuit: U.S. jury
(Reuters) - GlaxoSmithKline must pay $3 million to a woman who sued the drug company over the death of her husband, a lawyer who committed suicide after taking a generic version of the antidepressant Paxil, a U.S. jury said on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - April 20, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Not Just for Attention: Stop Teen Suicide
The subject of depression and suicide, especially in the case of children and teens, is a tremendous concern. Unfortunately, many cases go missed not necessarily because those surrounding these young people don’t care or pay enough attention to them, but more because they aren’t aware of what to look out for. I am a suicide survivor. I also grew up with a suicidal mother and witnessed a peer successfully commit suicide, ironically, when I was in the emergency room beside her being treated for the same thing. I was saved, while her family still mourns for her. These experiences, including the fact that my twelve...
Source: Psych Central - March 29, 2017 Category: Psychiatry Authors: Chynna Laird Tags: Antidepressants Children and Teens Depression Medications Personal Stories Self-Esteem Stress Suicide Therapists Spill Treatment Anxiety Coping Skills Depression Mood Depressive Episode Major Depressive Disorder Monoamine Oxi Source Type: news

NeuroBreak: Opioid Scripts Down at the VA; Paxil on Trial
(MedPage Today) -- News and commentary from the world of neurology and neuroscience (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - March 14, 2017 Category: Geriatrics Source Type: news

Lupin launches generic anti-depression drug in US
The company "announced the launch of generic paxil CR extended release tablets, 12.5 mg, 25 mg and 37.5 mg, having received an approval from the USFDA earlier (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 7, 2017 Category: Pharmaceuticals Source Type: news

Paxil (Paroxetine Hydrochloride) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news

Paxil-CR (Paroxetine Hydrochloride) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news

Brisdelle (Paroxetine Capsules 7.5 mg) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news

Pexeva (Paroxetine Mesylate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 15, 2016 Category: Drugs & Pharmacology Source Type: news

Falsified drug studies led to millions of children receiving dangerous antidepressants
(NaturalNews) In 2001, the pharmaceutical company SmithKline Beecham (now GlaxoSmithKline) published a trial known as Study 329, which claimed that the drug paroxetine – known as Paxil or Seroxat – was "generally well tolerated" and that it helped cure depression in children... (Source: NaturalNews.com)
Source: NaturalNews.com - August 30, 2016 Category: Consumer Health News Source Type: news

3 Drugs with the Most Severe Side Effects
Image Source Drugs have been known to have some sort of side effects on patients. Most of them are not often discussed in the health tabloids. While other drugs have side effects that are very nominal when compared to the benefits the patient derives from their usage, others have side effects that can impact the lives of their users forever. The most common side effects people experience from drug usage are gastrointestinal related issues which include constipation, nausea, and vomiting. Some other drugs can leave you feeling tired and dizzy for a short period of time. Combining these drugs with simple aspirin will usuall...
Source: Healthy Living - The Huffington Post - August 19, 2016 Category: Consumer Health News Source Type: news

Comparative risk of hip fractures in elderly nursing home patients with depression using paroxetine and other selective serotonin reuptake inhibitors - Bali V, Chatterjee S, Johnson ML, Chen H, Carnahan RM, Aparasu RR.
AIM: To evaluate comparative safety of paroxetine and other selective serotonin reuptake inhibitors (SSRIs) for the risk of hip fractures. Patients & methods: A propensity score-matched retrospective cohort study was conducted using 2007-2010 Minimum Data ... (Source: SafetyLit)
Source: SafetyLit - July 28, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Study Defends Antidepressant Use In Pregnancy Despite Birth Defect Risks
While SSRI antidepressants are arguably still the most consumed drug class in the US, sales peaked in 2008 and have declined by four percent every year since, according to Research and Markets. There are many reasons for declining SSRI sales from unwanted side effects like weight gain and sexual dysfunction to "Prozac Poop-out" in which patients develop tolerance and the pills quit working. Still, a major reason for declining sales are SSRI's strong links to suicide and birth defects. In 2004, the FDA added "Black Box" warnings to SRRIs, highlighting suicide risks and the need for close monitoring of...
Source: Healthy Living - The Huffington Post - July 26, 2016 Category: Consumer Health News Source Type: news

Both paroxetine and impramine appear to be ineffective in adolescents with major depression, furthermore doubts have risen about their safety
Adolescents suffering from major depression often receive treatment with antidepressants. However the evidence for the efficacy of both newer antidepressants and tricyclic antidepressants in major depression in adolescence is very limited. Systematic reviews1 found a statistically significant difference in efficacy in favour of antidepressants versus placebo, which was not clinically relevant. However, they concluded that the large majority of studies on this topic shows serious methodological flaws, selecting patients with advertisements, excluding patients with suicide r...
Source: Current Awareness Service for Health (CASH) - July 12, 2016 Category: Consumer Health News Source Type: news

paroxetine (Brisdelle)
Title: paroxetine (Brisdelle)Category: MedicationsCreated: 2/24/2015 12:00:00 AMLast Editorial Review: 7/8/2016 12:00:00 AM (Source: MedicineNet Menopause General)
Source: MedicineNet Menopause General - July 8, 2016 Category: Primary Care Source Type: news

Fentanyl can cause serotonin syndrome
3.5 out of 5 stars Serotonin Syndrome Induced by Fentanyl in a Child: Case Report. Robles LA. Clin Neuropharmacol 2015 Sept-Oct;38:206-8. Abstract When many clinicians think of serotonin syndrome (SS), they consider the usual suspects: Selective Serotonin Uptake Inhibitors (SSRIs) Citalopram Fluoxetine Sertraline Escitalopram Paroxetine Serotonin-Norepinephrine Reuptake Inhibitors Venlafaxine Duloxetine Antidepressants Trazodone Buspirone Clomipramine Aside from these common culprits, there are other commonly used drugs whose clear association with serotonin syndrome is less-often realized: Fentanyl ...
Source: The Poison Review - July 8, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical fentanyl opioid serotonin syndrome Source Type: news

Depression blood test could lead to personalised treatments
Conclusion This study shows how a new blood test in development can help identify people with depression who are most and least likely to benefit from antidepressants. While promising, the test is far from perfect. For example, it missed 39-43% of non-responders, meaning these people would continue to receive standard antidepressant treatment that is unlikely to work for them. A large proportion of patients (22-38%) also fell into the "intermediate" group who were neither responders nor non-responders, so the test wasn't too useful here. This means there is a significant proportion of people with...
Source: NHS News Feed - June 7, 2016 Category: Consumer Health News Tags: Mental health Medication Source Type: news

Antidepressants linked to premature births
(NaturalNews) Even though studies have already linked SSRI use during pregnancy to birth defects and autism in children, the pills are continually and dangerously prescribed to pregnant women. Common SSRIs like Prozac, Paxil and Zoloft artificially increase serotonin levels in the... (Source: NaturalNews.com)
Source: NaturalNews.com - May 28, 2016 Category: Consumer Health News Source Type: news

If you use Benadryl, Paxil, Dramamine it's REALLY time to stop: definite links to dementia, cognitive damage found with these OTC allergy drugs
(NaturalNews) Over-the-counter drugs, many of them formerly only available by prescription, are in abundance, and they supposedly treat a wide range of conditions and minor illnesses. But new research shows that many of these come with a host of side effects and potential side effects... (Source: NaturalNews.com)
Source: NaturalNews.com - April 29, 2016 Category: Consumer Health News Source Type: news

Researchers visualize brain's serotonin pump, provide blueprint for new, more effective SSRIs
Researchers have uncovered remarkably detailed 3-D views of one of the most important transporters in the brain -- the serotonin transporter. Their study provides fresh insight into how citalopram and paroxetine, two of the most widely prescribed selective serotonin reuptake inhibitors, or SSRIs, interact with and inhibit serotonin transport. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 6, 2016 Category: Science Source Type: news

Researchers visualize brain's serotonin pump, provide blueprint for new, more effective SSRIs
(Oregon Health & Science University) Researchers at Oregon Health & Science University's Vollum Institute have uncovered remarkably detailed 3-D views of one of the most important transporters in the brain -- the serotonin transporter. Their study, published online today in the journal Nature, provides fresh insight into how citalopram and paroxetine, two of the most widely prescribed selective serotonin reuptake inhibitors, or SSRIs, interact with and inhibit serotonin transport. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 6, 2016 Category: Biology Source Type: news

Should Paxil be banned? The only 'evidence' of effectiveness was ghostwritten by Glaxo Smith Kline's public relations firm
(NaturalNews) In 2001, a study was published in the Journal of the American Academy of Child and Adolescent Psychiatry, showing that the SSRI antidepressant paroxetine – sold under the names Paxil, Aropax and Seroxat – was safe, well tolerated and effective for the treatment... (Source: NaturalNews.com)
Source: NaturalNews.com - March 29, 2016 Category: Consumer Health News Source Type: news

Treatment for Seasonal Affective Disorder
Seasonal affective disorder(SAD) — also known as the winter blues or winter depression — is a seasonal but serious disorder that impacts many people with the changing of the seasons (from fall into winter, or from spring into summer). Luckily there are a number of effective treatment options for anyone who is suffering from seasonal affective disorder. Light Boxes Research has found that the majority of those suffering from the winter blues experienced relief solely from the regular use of light boxes. Light boxes emit high intensities of light of 2,500 to 10,000 lux (as compared to a normal light fixture that ...
Source: Psych Central - March 11, 2016 Category: Psychiatry Authors: John M. Grohol, Psy.D. Tags: Antidepressants Depression Disorders Medications Psychotherapy Seasonal Affective Disorder Treatment help for the winter blues help for winter depression seasonal affective disorder treatment treatment for sad treatment for seasonal Source Type: news

Comorbid tics have no effect on response to cognitive-behavioural therapy in youth with obsessive-compulsive disorder
Tic-related obsessive-compulsive disorder (OCD) is a DSM-5 diagnostic subtype that is estimated to occur in 10–40% of cases with childhood onset.1 Studies comparing tic-related and non-tic-related OCD have found consistent differences in sex, onset age, comorbidity and course, but inconsistent differences in OCD symptoms and prevalence of OCD and tics in first-degree relatives.1 ,2 Medication trials have indicated that tic-related OCD is less responsive to sertraline, fluvoxamine and paroxetine; however, tic history appears to have no effect on the response of OCD in youth to either ...
Source: Current Awareness Service for Health (CASH) - March 4, 2016 Category: Consumer Health News Source Type: news

Antidepressant may improve cognitive symptoms in people with HIV
The antidepressant paroxetine modestly improves decision-making and reaction time, and suppresses inflammation in people with HIV-associated cognitive impairment, physicians report at the conclusion of a small, placebo-controlled clinical trial. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 25, 2016 Category: Science Source Type: news

Antidepressant may improve cognitive symptoms in people with HIV
(Johns Hopkins Medicine) In a small, placebo-controlled clinical trial, Johns Hopkins physicians report that the antidepressant paroxetine modestly improves decision-making and reaction time, and suppresses inflammation in people with HIV-associated cognitive impairment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 25, 2016 Category: Global & Universal Source Type: news

How Can Paxil Help Generalized Anxiety Disorder?
Paxil (paroxetine) is an antidepressant medication in the same class as Prozac and Zoloft. It is also used to treat generalized anxiety disorder. (Source: About.com Mental Health)
Source: About.com Mental Health - February 17, 2016 Category: Psychiatry Tags: health Source Type: news

What Are Current Treatments for Postpartum Depression?
Discussion Postpartum depression affects 10 to 20% of women after delivery, but less than half of these women are detected. Postpartum depression is defined as major depressive episodes with symptom onset during pregnancy or in the first four weeks following delivery. There is recognition that symptoms may begin later after delivery but the mother would not be diagnosed with PPD. PPD is distinct from postpartum blues which occur in 50 to 80% of new mothers. They occur within 1 to 2 days of delivery and resolve within 10-14 days of delivery. Symptoms include anxiety, depression, irritability, tearfulness, poor sleep, and a...
Source: PediatricEducation.org - February 15, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Antidepressants linked to suicide and aggression in teens
ConclusionPerhaps the most troubling aspect of this paper is not the increased risk of suicidal thoughts in young people, as that has been known for many years. What is worrying is the researchers’ conclusion that they are unable to tell the true extent of harms from antidepressants, because of poor data collection and availability.RCTs are designed to test the effects of treatments with as little bias as possible. However, if the right data on adverse effects is not collected in the trials, or is not made public, we cannot balance the benefits and risks of treatment in a fair and transparent way. According to the da...
Source: NHS News Feed - January 28, 2016 Category: Consumer Health News Tags: Mental health Medication Source Type: news

Anti-depressants for teens: A second look
This study highlights the importance of talking to your trusted doctor about the things you hear before just accepting the version of results presented to you. As a doctor, I look forward to more studies that re-examine our current understanding of research data. I hope they will help provide the important information I need to best guide my patients. Related Post:Teen suicide tries increased after FDA toughened…Teens with upbeat friends may have better emotional healthAntidepressants cause minimal weight gainThe placebo effect: Amazing and realHeads up, parents: New study with important information…The post ...
Source: New Harvard Health Information - January 22, 2016 Category: Consumer Health News Authors: Nandini Mani, MD Tags: Anxiety and Depression Behavioral Health Children's Health Parenting antidepressants teens Source Type: news

GSK to Face First Trial Over Adult Paxil Suicide
A U.S. District Judge declined to rule on a pair of motions filed by GSK defense lawyers, meaning the drugmaker will head to court to face claims that a generic version of its Paxil antidepressant caused an Illinois man's suicide. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - January 15, 2016 Category: Pharmaceuticals Source Type: news

Widely Prescribed Antidepressant Linked to Birth DefectsWidely Prescribed Antidepressant Linked to Birth Defects
Use of the selective serotonin reuptake inhibitor paroxetine during pregnancy may increase the risk of congenital and cardiac malformations in children, new research shows. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 14, 2016 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Paroxetine in early pregnancy once again linked to birth defects
(Reuters Health) - Women who take the antidepressant paroxetine (Paxil, Seroxat) early in pregnancy may be more likely to have babies with birth defects, a review of previous research suggests. (Source: Reuters: Health)
Source: Reuters: Health - January 13, 2016 Category: Consumer Health News Tags: healthNews Source Type: news