Men conceived by IVF 'may inherit sperm problems'

Conclusion This small cross-sectional study aimed to assess the semen quality of young men who were conceived by ICSI. The study found that when compared with men conceived naturally, men conceived by ICSI had a lower average sperm concentration, total sperm count, and total motile sperm count. This effect remained after the team adjusted for potential confounders. This finding supports concerns that the infertility of a father could be passed on to male offspring, but does not prove it. The study does not rule in or out the possibility of the difference being a result of the ICSI procedure itself or an unrelated issue.  This research has limitations that should be mentioned: These findings are based on a very small study population, and the same effect may not have been seen in a larger study. Of all the men conceived by ICSI invited to take part in the study, only 37.5% agreed. The researchers have provided a breakdown of those who declined, but it is possible that the 45 men and 21 families that declined did so because the young men do not have fertility issues and this would greatly alter the result. A number of confounders have been considered in the analysis. However, there is still a chance of residual confounding in the model or that important factors were not addressed. The samples were only provided on one occasion so may not be an accurate representation. There are too many limitations to draw any firm conclusions from this re...
Source: NHS News Feed - Category: Consumer Health News Tags: Pregnancy/child Medical practice Source Type: news

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Conclusion: A considerable knowledge gap about the factors that influence fertility was identified in reproductive-age individuals in an urban area of Thailand. This issue should be urgently addressed by promoting fertility awareness through education, discussions about social perceptions regarding fertility, and reliable sources of knowledge. PMID: 29662824 [PubMed]
Source: Clinical and Experimental Reproductive Medicine - Category: Reproduction Medicine Tags: Clin Exp Reprod Med Source Type: research
ConclusionsPerceived stress, infertility‐related stress, and cortisol levels were not associated with IVF cycle outcomes. These findings are potentially reassuring to women undergoing fertility treatment with concerns about the influence of stress on their treatment outcome.This article is protected by copyright. All rights reserved.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: Original Research Article Source Type: research
Authors: Purewal S, Chapman SCE, van den Akker OBA Abstract OBJECTIVE: Lifestyle (smoking, drinking alcohol) and body mass index (BMI) predictors of successful outcomes in assisted reproductive technology (ART) treatments were examined in this meta-analysis. METHOD: A bibliographic search was undertaken using six databases. The review was informed by PRISMA/MOOSE guidelines. Meta-analytic data were analysed using random effects models. RESULTS: We included 77 studies examining effects of BMI, smoking and drinking alcohol. Patients with a BMI =25 OR = 1.219 (95% CI:1.128-1.319, z ...
Source: Journal of Psychosomatic Obstetrics and Gynaecology - Category: OBGYN Tags: J Psychosom Obstet Gynaecol Source Type: research
This report presents baseline estimates of the use of these preventive services before the publication of QFP that can be used to monitor progress toward improving the quality of preventive care received by women and men of reproductive age. PERIOD COVERED: 2011-2013. DESCRIPTION OF THE SYSTEM: Three surveillance systems were used to document receipt of preventive health services among women and men of reproductive age as recommended in QFP. The National Survey of Family Growth (NSFG) collects data on factors that influence reproductive health in the United States since 1973, with a focus on fertility, sexual act...
Source: MMWR Surveill Summ - Category: Epidemiology Authors: Tags: MMWR Surveill Summ Source Type: research
Authors: Salih Joelsson L, Tydén T, Wanggren K, Georgakis MK, Stern J, Berglund A, Skalkidou A Abstract BACKGROUND: Infertility has been associated with psychological distress, but whether these symptoms persist after achieving pregnancy via assisted reproductive technology (ART) remains unclear. We compared the prevalence of anxiety and depressive symptoms between women seeking for infertility treatment and women who conceived after ART or naturally. METHODS: Four hundred and sixty-eight sub-fertile non-pregnant women, 2972 naturally pregnant women and 143 women pregnant after ART completed a questionna...
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
Conclusions Women pregnant after ART showed no difference in anxiety and depressive symptoms compared to naturally pregnant women. However, early psychological counseling and management of unhealthy lifestyle behaviors for sub-fertile women may be advisable, particularly for women with a previous history of psychiatric diagnosis.
Source: European Psychiatry - Category: Psychiatry Source Type: research
Discussion Of the 30 different microbes which can be transmitted by sexual contact, 8 have the greatest incidence of transmitting disease. Four are curable (Chlamydia, Gonorrhea, Syphilis and Trichomoniasis) and 4 are incurable at present (Hepatitis B, Herpes simplex virus (HSV), Human immunodeficiency virus (HIV) and Human papillomavirus (HPV)). Sexually transmitted infections (STIs) are important as they can cause: Increased rates of acquisition of other STIs (ie HSV and syphilis increase the rate of HIV infection acquisition) Pelvic inflammatory disease and infertility Stillbirth and neonatal death Neonatal morbidity i...
Source: - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
AbstractSTUDY QUESTIONWhat is the impact of preconception lifestyle interventions on live birth, birth weight and pregnancy rate?SUMMARY ANSWERLifestyle interventions showed benefits for weight loss and increased natural pregnancy rate, but not for live birth or birth weight.WHAT IS KNOWN ALREADYEvidence on the practice and content of preconception counseling and interventions is variable and limited.STUDY DESIGN, SIZE, DURATIONSystematic review and meta-analysis (MA). Main search terms were those related to preconception lifestyle. Database searched were Ovid MEDLINE(R), EBM Reviews, PsycINFO, EMBASE and CINAHL Plus. No l...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research
Conclusions: Certain PFASs are associated with abnormal menstruation in humans. Received: 08 October 2016 Revised: 03 January 2017 Accepted: 25 January 2017 Published: 22 June 2017 Address correspondence to J. Zhang, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. Telephone: 86-21-2507 8871. E-mail:, or Y. Tao, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. Telephone: 86-21-663846590-776806. E-mail: Supplemental Material is available online (
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Conclusion: Prenatal urinary BPA concentration was associated with some aspects of child behavior in this cohort, and some associations were stronger among boys. Received: 18 August 2016 Revised: 09 December 2016 Accepted: 12 December 2016 Published: 16 June 2017 Address correspondence to Joseph M. Braun, Department of Epidemiology, Box G-S121-2, Brown University, Providence, RI 02912 USA. Telephone: (401) 863-5397. E-mail: Supplemental Material is available online ( The authors declare they have no actual or potential competing fi...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
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