U-Shaped Association between Plasma Manganese Levels and Type 2 Diabetes

Conclusions: Our results suggested a U-shaped association between plasma manganese and T2D; both low and high levels of plasma manganese were associated with higher odds of newly diagnosed T2D. The U-shaped association was not modified by MnSOD rs4880 polymorphism. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Shan Z, Chen S, Sun T, Luo C, Guo Y, Yu X, Yang W, Hu FB, Liu L. U-Shaped Association between Plasma Manganese Levels and Type 2 Diabetes. Environ Health Perspect; http://dx.doi.org/10.1289/EHP176 Received: 20 October 2015 Revised: 4 January 2016 Accepted: 13 May 2016 Published: 3 June 2016 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehp508@niehs.nih.gov. Our staff will work with you to assess and meet y...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Article Source Type: research