Abstract B23: Epigenetic control of prostate epithelial stem cell differentiation

Discussion: By studying highly enriched cell populations in different model systems, all of which are derived from primary human tissues, we have built up a complex picture of epigenetic regulation of gene expression during differentiation of human prostate. Many of these essential functions are related to similar functions in developing prostate tissue, but are often characterized by phenotypic plasticity, where the differentiated products of asymmetric division (self-renewal) can revert to a stem-like state.Citation Format: Norman James Maitland, John Packer. Epigenetic control of prostate epithelial stem cell differentiation. [abstract]. In: Proceedings of the AACR Special Conference: Developmental Biology and Cancer; Nov 30-Dec 3, 2015; Boston, MA. Philadelphia (PA): AACR; Mol Cancer Res 2016;14(4_Suppl):Abstract nr B23.
Source: Molecular Cancer Research - Category: Cancer & Oncology Authors: Tags: Stem Cell of Origin: Poster Presentations - Proffered Abstracts Source Type: research