Detoxification and underlying mechanisms towards toxic alkaloids by Traditional Chinese Medicine processing: A comprehensive review

CONCLUSION: Through this exploration, we review toxic alkaloids and the mechanisms underlying their toxicity, discuss methods to reduce toxicity, and unravel the intricate mechanisms behind detoxification. These offers insights into the quality control of herbs containing toxic alkaloids, safe and rational use of alkaloid-rich TCMs in clinics, new strategies for drug discovery and development, and ultimately helping improve the quality of life for millions of people.PMID:38703661 | DOI:10.1016/j.phymed.2024.155623

Source: Cancer Control - May 4, 2024 Category: Cancer & Oncology Authors: Qiyuan Shan Wei Yu Qiongfang Xu Ruina Liu Shuye Ying Jie Dong Yini Bao Qiang Lyu Changcheng Shi Junjie Xia Jing Tang Haodan Kuang Kuilong Wang Gang Tian Gang Cao Source Type: research