Human umbilical cord mesenchymal stem cell-derived exosomes alleviate the severity of experimental autoimmune encephalomyelitis and enhance lag-3 expression on foxp3 + CD4 + T cells
CONCLUSIONS: These results suggest that hUMSCs-Exs could be a promising anti-inflammatory agent to regulate T-cell responses in EAE and other autoimmune diseases. However, further research is necessary to fully understand the underlying mechanisms and Lag-3's precise role in these conditions.PMID:38627337 | DOI:10.1007/s11033-024-09433-5
Source: Molecular Biology Reports - Category: Molecular Biology Authors: Adel Mohammadzadeh Masoud Lahouty Hamed Charkhian Arash Adamnejad Ghafour Sahand Moazzendizaji Jafar Rezaei Shahriar Alipour Vahid Shafiei Irannejad Mohammad Hassan Khadem Ansari Source Type: research
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