The Crown Jewel: Checkpoint Inhibition in Unresectable Cutaneous Squamous Cell Carcinoma

This is a complex case1 requiring multidisciplinary assessment. Given his non-melanoma skin cancer history, consideration should be given to whether the biopsy is representative of the entire lesion. We would not recommend upfront surgery for this locally advanced cutaneous squamous cell carcinoma with likely transdural spread and parenchymal brain and posterior sagittal sinus involvement. The survival for these cases is poor,2 and resection of the posterior sagittal sinus carries a high risk of venous infarction.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Gray Zone Expert Opinion Source Type: research