Biologically Informed Polygenic Scores for Brain Insulin Receptor Network Are Associated with Cardiometabolic Risk Markers and Diabetes in Women

CONCLUSION: hePRS-IR is associated with sex-specific differences in cardiometabolic risk factor profiles including impaired glucose regulation, abnormal metabolic markers, and unfavorable body composition in women.PMID:38527457 | DOI:10.4093/dmj.2023.0039

Source: Diabetes and Metabolism Journal - March 25, 2024 Category: Endocrinology Authors: Jannica S Selenius Patricia P Silveira Mikaela von Bonsdorff Jari Lahti Hannu Koistinen Riitta Koistinen Markku Sepp älä Johan G Eriksson Niko S Wasenius Source Type: research