CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction

CONCLUSIONS: The diminished de novo lipogenesis, which is associated with increased acetyl-CoA, acylcarnitine, and butyrate metabolite levels, could contribute to safeguarding not only the peripheral system but also the aging brain. By mimicking the effects of ketogenic diets, CMS121 holds promise for metabolic diseases such as obesity and diabetes, since these diets are hard to follow over the long term.PMID:38517358 | DOI:10.18632/aging.205673

Source: Aging - March 22, 2024 Category: Biomedical Science Authors: Alcir L Dafre Saadia Zahid Jessica Jorge Probst Antonio Currais Jingting Yu David Schubert Pamela Maher Source Type: research