Effect of melatonin on reproductive function in propylthiouracil induced hypothyroidism in adult male rats

CONCLUSIONS: Based on the study findings, melatonin could mitigate gonadal dysfunction induced by hypothyroidism by improving several components of semen analysis, such as sperm motility and sperm viability, as well as by enhancing testosterone production focusing on oxidative and inflammatory stress as the underlying mechanisms.PMID:38497875 | DOI:10.26355/eurrev_202403_35606

Source: Pharmacological Reviews - March 18, 2024 Category: Drugs & Pharmacology Authors: W Ezzat W K Abdelbasset R S Hussien A R Azab A Sulieman S Yousry Source Type: research