Standard medical therapy with vs. without nebulised magnesium for children with asthma decompensation

Conclusion: In children with asthma exacerbation, treatment with nebulised magnesium and SMT was associated with a statistically significant, but small improvement in predicted PEFR and respiratory rate, as compared with SMT alone.What is Known:• Magnesium sulfate has bronchodilating properties and aids in the treatment of asthma exacerbation when administered intravenously.• There is no significant evidence of benefit of nebulised magnesium as an adjunct therapy to the standard medical treatment for children with asthma exacerbations.What is New:• Our study suggests nebulised magnesium sulfate may have a statistically significant, but small benefit in respiratory rate and peak expiratory flow rate. The addition of nebulised magnesium does not seem to increase adverse events.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research