LT and SOX9 expression are associated with gene sets that distinguish Merkel cell polyomavirus-positive and -negative Merkel cell carcinoma

CONCLUSIONS: Tumours with weak expression of LT tend to co-express genes related to squamous differentiation and cell cycle, and to have a higher mutational burden. These findings are congruent with those of earlier studies.PMID:38261397 | DOI:10.1093/bjd/ljae033

Source: The British Journal of Dermatology - January 23, 2024 Category: Dermatology Authors: Juan Torre-Castro Marta Rodr íguez Ruth Alonso-Alonso Mar ía Dolores Mendoza Cembranos Jes ús Frutos Díaz-Alejo Marcos Rebollo-Gonz ález Jennifer Borreg ón Laura N ájera Botello Ignacio Mahillo-Fern ández Mathab Samimi Thibault Kervarrec Luis Requ Source Type: research