Recapitulation of Human Pathophysiology and Identification of Forensic Biomarkers in a Translational Model of Chlorine Inhalation Injury

In this study, we developed a translational swine model that recapitulates key features of human Cl2 inhalation injury and is suitable for testing medical countermeasures, and validated chlorinated fatty acids and protein adducts as biomarkers of Cl2 inhalation.PMID:38318664 | DOI:10.1152/ajplung.00162.2023

Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - February 6, 2024 Category: Cytology Authors: Satyanarayana Achanta Michael A Gentile Carolyn J Albert Kevin A Schulte Brooke G Pantazides Brian S Crow Jennifer Quinones-Gonzalez Jonas W Perez David A Ford Rakesh P Patel Thomas A Blake Michael D Gunn Sven E Jordt Source Type: research