S-9-PAHSA's neuroprotective effect mediated by CAIII suppresses apoptosis and oxidative stress in a mouse model of type 2 diabetes
CONCLUSION: S-9-PAHSA mediated by CAIII has the potential to exert a neuroprotective effect by suppressing apoptosis and oxidative stress in neuronal cells exposed to diabetic conditions. Furthermore, S-9-PAHSA has the capability to reduce fasting blood glucose and LDL levels and enhance insulin sensitivity in mice fed with HFD.PMID:38332538 | PMC:PMC10853598 | DOI:10.1111/cns.14594
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Jian-Tao Wang Xin-Ru Wang Jiao-Qi Ren Jin-Hong Lin Zhong-Yu Yu Shan-Shan Huang Yue Hu Jia-Yu Fu Meng Wang Yan-Li Zhang Xue-Chun Wang Jing-Chun Guo Ji-Chang Xiao Hou-Guang Zhou Source Type: research
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