Drug-drug interaction assessment based on a large-scale spontaneous reporting system for hepato- and renal-toxicity, and thrombocytopenia with concomitant low-dose methotrexate and analgesics use

CONCLUSIONS: Studies using spontaneous reporting systems have limitations such as reporting bias or lack of patient background; however, the results of our comprehensive analysis support the results of previous clinical or epidemiological studies. This study also demonstrated the usefulness of FAERS for DDI assessment.PMID:38303016 | PMC:PMC10832291 | DOI:10.1186/s40360-024-00738-6
Source: BMC Pharmacology and Toxicology - Category: Drugs & Pharmacology Authors: Source Type: research