Wrong lessons in lipidology : Eradicating LDL is not our goal !

15 % of body weight is fat. (10kg) Out of which just 250 mg of cholesterol is streaming in blood. We must understand fat, lipid and cholesterol are different entities. LDL is obviously a target against atherosclerosis. While the total body fat seems to do little in determining blood cholesterol levels, what is more scientifically shocking is the slope of curve between blood LDL levels and plaque burden is rarely linear. Mind you, LDL constitutes .000025% of total fat. We have many other targets in dyslipidemia like free cholesterol, harmful fatty acids, remnant cholesterol, TGLs, dysfunctional HDLs LDL is not innocent Cone electron microscopic Image : A macrophage after a diet full of LDL molecules There are innumerable evidence for LDL, being the enemy number one in human atherosclerosis .It don’t know but, it fully deserve the name bad cholesterol.It looks like it may be counting its last few decades, as the whole pharma industry is activated to destroy this physiological molecule that carries some critical functions in our body. In one of the hyper-educated debate, I asked how low we can bring LDL down ? One leading professor of lipidology with a H index possibly crossing his LDL levels, said, we can go as low as possible , even to zero. He argued for possible eradication of this heinous molecule. No surprise, there was a thunderous applause from the industry benches. How to go about lowering the LDL ? Statins are the first line drugs. We have ...
Source: Dr.S.Venkatesan MD - Category: Cardiology Authors: Tags: Uncategorized cut off value for ldl esc aha guidlines for lipids functions of ldl molecule good and bad cholesterol how low ldl can go inclisiron lipid metabolism lipidology pcsk inhibitors repatha Source Type: blogs