Characteristics of cervical cancer caused by the human papillomavirus 18 and its genetic variations in Vietnamese women

CONCLUSION: Patients with a single HPV18 infection have a higher risk of cervical cancer than those infected with HPV18 and other high-risk strains simultaneously. HPV18 single-infection, on the other hand, had considerably higher incidences of L/HSIL, SCC, AC, and CIS than HPV18 co-infection. The HPV18 strain that was found in Vietnam belonged to lineage A (A1 and A5), which contains several oncogene mutations.PMID:38176603 | DOI:10.1016/j.meegid.2023.105546
Source: Infection, Genetics and Evolution - Category: Genetics & Stem Cells Authors: Source Type: research