High-dose vitamin D3 supplementation in pregnancy and risk of neurodevelopmental disorders in the children at age 10 - A randomized clinical trial

CONCLUSIONS: Higher maternal pre-intervention 25(OH)D was associated with a decreased risk of autism, lower autistic symptom load, and decreased risk of ADHD diagnosis, but high-dose vitamin D3 supplementation in pregnancy had no effect on risk of autism and ADHD.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT00856947 URL: https://classic.CLINICALTRIALS: gov/ct2/show/NCT00856947?term=NCT00856947&draw=2&rank=1.PMID:38072183 | DOI:10.1016/j.ajcnut.2023.12.002

Source: The American Journal of Clinical Nutrition - December 10, 2023 Category: Nutrition Authors: Kristina Aagaard Jens Richardt M øllegaard Jepsen Astrid Sevelsted David Horner Rebecca Vinding Julie B øjstrup Rosenberg Nicklas Brustad Anders Eliasen Parisa Mohammadzadeh Nilofar F ølsgaard Mar ía Hernández-Lorca Birgitte Fagerlund Birte Y Glenth Source Type: research