Assessing the hypolipidemic and gastro-liver protective activity of herbal combination with emphasis on PPI amid selected multiple antihypertensive drug combination in experimental animal models

CONCLUSIONS: CThis investigation reported that antihypertensive drugs did not produce gastrointestinal (GI) toxicity, and the morphological structure of the organ was not changed. So, it could be concluded that the herbal combination used in this experiment has a promising role in controlling lipid profile, liver function, and antiulcer effects. Moreover, multiple drug therapy for hypertension does not cause any harm to the stomach. Further investigations might be carried out on a larger scale to make these statements more valid.PMID:38039033 | DOI:10.26355/eurrev_202311_34471

Source: Pharmacological Reviews - December 1, 2023 Category: Drugs & Pharmacology Authors: R P Monisa A K Azad I Rahma J T Israt A Shopnil A K Ayaz U H Taqweem T Aziz A Metab H A Thamer F A Abdullah Source Type: research