Therapeutic potential of [ < sup > 177 < /sup > Lu]Lu-DOTAGA-FAPi dimers in metastatic breast cancer patients with limited treatment options: efficacy and safety assessment

CONCLUSION: The findings suggest that [177Lu]Lu-DOTAGA.FAPi dimer therapy is well-tolerated, safe, and effective for treating end-stage metastatic breast cancer patients. [177Lu]Lu-DOTAGA.FAPi dimer treatment demonstrated promising efficacy in patients with advanced breast cancer, as indicated by high disease control rates, favorable response outcomes, and acceptable safety profile. Further research and longer follow-up are warranted to assess long-term outcomes and validate these findings.PMID:37932560 | DOI:10.1007/s00259-023-06482-z

Source: Cancer Control - November 6, 2023 Category: Cancer & Oncology Authors: Madhav P Yadav Sanjana Ballal Marcel Martin Frank Roesch Swayamjeet Satapathy Euy S Moon Madhavi Tripathi Ajay Gogia Chandrasekhar Bal Source Type: research