The evaluation of the possibility of Li-Fraumeni syndrome in cancer patients in East Azarbaijan Province of Iran

CONCLUSION: Our results show that there were no mutations in exons 5-8 of the TP53 gene as an indication of LFS possibility in these families. Further studies are needed to be done in a bigger population, and Next-Generation Sequencing (NGS) needs to be done to evaluate the whole genome of these patients to complete our data.PMID:37801337 | DOI:10.1080/15257770.2023.2264361

Source: Nucleosides, Nucleotides and Nucleic Acids - October 6, 2023 Category: Biochemistry Authors: Maryam Esmaeilzadeh Aghjeh Mohammad Ali Hosseinpour Feizi Reza Safaralizadeh Abbas Ali Hosseinpour Feizi Nasser Pouladi Source Type: research