Risk of metachronous colorectal cancer after colectomy for first colon cancer in Lynch syndrome: multicenter retrospective study in Japan

CONCLUSIONS: To reduce the incidence of mCRC, patients with genetically diagnosed LS and fCC, preferentially located in the left-sided colon, may need to undergo more extended colectomy than that usually performed in Japan. However, such extended colectomy should be counterbalanced with favorable overall survival and actual risk of mCRC development.PMID:37752370 | DOI:10.1007/s10147-023-02412-z

Source: Clinical Colorectal Cancer - September 26, 2023 Category: Cancer & Oncology Authors: Kenichi Chikatani Hideyuki Ishida Yoshiko Mori Takeshi Nakajima Arisa Ueki Kiwamu Akagi Akinari Takao Masayoshi Yamada Fumitaka Taniguchi Koji Komori Kazuhito Sasaki Tomoya Sudo Yasuyuki Miyakura Akiko Chino Tatsuro Yamaguchi Kohji Tanakaya Naohiro Tomita Source Type: research