Non-criteria autoantibodies in antiphospholipid syndrome may be associated with underlying disease activity

ConclusionSystemic lupus erythematosus (SLE) is the most commonly associated disease with APS, being present in approximately 35% of cases  [1]. Since the majority of the patient group in our study had APS that was secondary to SLE, non-criteria antibody positivity may be linked to the immunological activity of SLE. Large multicenter studies are necessary to investigate the clinical significance of isolated/combined positivity for criterion/non-criteria aPLs.
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research